THE ROLE OF GENERALIZED INTRAUTERINE INFECTION IN THE STRUCTURE OF CAUSES OF INTRAUTERINE FETUS AND INFANT FATALITY IN THE VINNYTSIA REGION
DOI:
https://doi.org/10.11603/1681-2727.2018.2.9034Keywords:
generalized intrauterine infection (GIUI), stillbirth, children born alive, infant fatality, placental changes.Abstract
The aim of the work – generalized intrauterine infection (GIUI) is the main cause of perinatal mortality (36 %) worldwide. According to data of the Ministry of Health, Ukraine, intrauterine infection (IUI) is in second place among the causes of infant mortality, and its incidence rate reaches 40-70 %. The aim of our study was to evaluate the role of GIUI in the structure of causes of intrauterine fetus and infant fatality in Vinnytsia region for the period since 2013 to 2016 and analyze the preconditions that contributed to their development.
Materials and methods.A retrospective, 626 protocols of autopsy of stillbirths and children who died in the first year of their life according to the data of Vinnytsia Regional Pathology and Autopsy Bureau for year 2013 to 2016 were analysed.Conclusions. GIUI is among the main causes of infant fatality and consists 25.3 % among the dead children. Among the main factors that aggravates the course of pregnancy and the condition of the fetus were chronic infectious diseases of the mother, inflammatory changes in the placenta. Multiple organ lesions and polietiology lesions in GIUI are factors that complicate on time in vivo clinical diagnosis, therefore in most of the cases, GIUI were posthumously diagnosed.
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