Revascularization in patients with high risk of eveloping the reperfusion syndrome
DOI:
https://doi.org/10.11603/2414-4533.2017.2.7740Keywords:
atherosclerotic occlusion, reperfusion syndrome, staged revascularization.Abstract
The aim of the work: to prevent reperfusion complications by conducting staged revascularization of aorto-femoral-popliteal segment in patients with high risk of developing the reperfusion syndrome.
Materials and Methods. The paper presents the results of examination and treatment of 31 patients with atherosclerotic lesion of aorta and main arteries of the lower extremities. The willingness of organism to developing the reperfusion complications was evaluated by content in blood serum C-reactive protein, lactate, level of endogenous intoxication, level intradermal blood flow to the rear foot. Preoperative preparation of patients included prolonged epidural anesthesia, leukapheresis session, antioxidant treatment, intravenous administration of drug Perftoran and Corvitin. Patients were divided into two groups by level of revascularization. Surgical intervention in patients of group I (17 patients) included combined reconstruction aorto-femoral and femoral-popliteal segments in the group II of patients (14 patients) reconstruction of these segments were made in two stages.
Results and Discussion. When conducting analysis of current perioperative period we found that the degree of manifestation the reperfusion syndrome after reconstructive surgery in patients of group II was 5.8 times lower than in patients of the group I. Revascularization of aorto-femoro-popliteal segment was stages, held against the backdrop of complex preoperative preparation and included a session leukapheresis, antioxidant therapy with intravenous drugs Perftoran and Corvitin allowed to reduce the incidence of reperfusion complications.
References
Venher, I.K., Kostiv, S.Ya, & Zarudnyi, O.M. (2005). Reperfisiinyi syndrom u patsiientiv z khronichnoiu krytychnoiu ishemiieiu pislia rekonstruktsii aterosklerotychnoi okliuzii aorty ta mahistralnykh arterii nyznikh kintsivok [Reperfusion syndrome in patients with chronic critical limb ischemia after reconstruction atherosclerotic occlusion of the aorta and main arteries of the lower extremities], Naykovyi visnyk uzhhorodskoho universytetu – Scientific Journal of Uzhhorod University, 24, 115-120 [in Ukrainian].
Venher, I.K., Yakymchuk, O.A., & Zarudna, O.I. (2010). Korektsiia eferentnoiu terapiieiu systemnoi zapalnoi vidpovidi u khvorykh na obliteruiuchyi ateroskleroz arterii nyzhnikh kintsivok [Correction efferent therapy systemic inflammatory response in patients with atherosclerosis of the arteries of the lower extremities]. Shpytalna khirurhiia – Hospital Surgery, 1, 83-86 [in Ukrainian].
Kazakov, U.V., Kargapolov, A.V., Kuks, P.V., Belov, I.V., & Kazakov, A.U. (2004). Autovenoznoe bedrenno-podkolennoe shuntirovanie u patsientov razlichnykh vozrastnikh grupp [Autovenous femoral-popliteal shunting in patients of different age groups]. Vestnik khirurgii – Journal of Surgery, 1, 32-35 [in Russian].
Kuznetsov, M.R., Koshkin, V.M., & Komov, K.V. (2005). Sovremennye aspekty diagnostiki, profilaktiki i lecheniya reprfusionnogo sindroma [Modern aspects of diagnosis, prevention and treatment of reperfusion syndrome]. Angiologiya i sosudistaya khirurgiya – Angiology and Vessel Surgery, 1, 133-143 [in Russian].
Neimark, M.I., & Merkulov, I.V. (2005). Anesteziya i intensivnaya terapiya s chirurgii aorty i ee vetvey: mongrafiya [Anesthesia and intensive care in aortic surgery and its branches: monograph]. Perozavodsk: Intelekt [in Russian].
Nikonenko, A.S., Hubka A.V., & Pertsov, V.I. (2005) Vybor metoda rekonstruktivnoy operetsii pri distalnoy okklyuzii arteriy nizhnikh konechnostey [The choice of the method of reconstructive surgery in the distal occlusion of arteries of the lower extremities]. Klinichna khirurgiya – Clinical Surgery, 4-5, 57-59 [in Russian].
Nikulnikov, P.I., Butsay, A.N., Ratushnyak, A.V., & Liksunov, A.V. (2013). Osobennosti khirurgicheskoy taktiki pri mnogourovnevykh oklyuzionno-stenoticheskikh porazheniyakh bedrenno-bertsovogo arterialnykh segmentov [Features of surgical tactics in multilevel occlusive-stenotic lesions of the femoral-abortive arterial segments]. Kharkivska chirurgichna shkola – Kharkiv Surgery School, 3, 148-151 [in Russian].
Laipanov, Kh.I.Kh.M., Sergienko, V.I., & Petrosyan, Ye.A. (2007). Protsesy perekesnogo okisleniya lipidov krovi pri ostroy ishemii i reperfusii konechnosti [Processes of lipid peroxidation in acute ischemia and reperfusion of the limb]. Novye infomatsionnye tekhnologii v meditsine, biologii, farmakologii i ekologii – New Information Technologies in Medicine, Biology, Pharmacology and Ecology, 2, 274- 176 [in Russian].
Spiridonov, A.A., Arekelyan, V.S., & Tutov, E.G. (2005). Khirurgicheskoe lechenie anevrism brushnoy aorty [Surgical treatment of aneurysms of the abdominal aorta]. Moscow [in Russian].
Cherr, G.S., & Hansen, K.J. (2001) Renal complications with aortic surgery. Semin. Vase. Surg. 14 (4), 118-121.
Kabaroudis, A., Gerassimidis, T., & Karamanos, D. (2003). Metabolic alteration of skeletal muscle tissue after prolonged acute ischemia and reperfusion (In Process Citation). J. Invest. Surg. 16 (4), 219-228.
Saita, Y., Yokoyama, Y., Nakamura, K., & Itoman, M., (2002). Protective effect of preconditioning against ischemia-induced reperfusion injury of sckeletal muscle how many preconditioning are appropriate? British Journal of Plastic Surgery, 55 (3), 241-245.
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