The effectiveness of surgical treatment of patients with respiratory symptoms of gastroesophageal reflux disease

Authors

  • M. R. Paranyak Odessa National Medical University
  • V. V. Grubnik Odessa National Medical University

DOI:

https://doi.org/10.11603/2414-4533.2017.2.7718

Keywords:

gastroesophageal reflux disease, laparoscopic fundoplication, extraesophageal manifestations, cough.

Abstract

The aim of the study: comparison of the effectiveness of conservative therapy and surgical treatment of patients with respiratory manifestations of gastroesophageal reflux disease and hiatal hernia.

Materials and Methods. 41 patients underwent laparoscopic Nissen fundoplication and 25 patients – conservative therapy of gastro­esophageal reflux disease. The results of the treatment were assessed using 24-hour pH-monitoring of the esophagus and the GERD-HRQL quality of life questionnaire. Likert heartburn intensity, intensity of coughing attacks according to 10-point visual analogue scale, quantitative index of coughing attacks for one day, symptom index of reflux cough were then made.

Results and Discussion. We established significantly better results (p <0.001) relative decrease in the frequency and intensity of cough in patients who performed laparoscopic fundoplication. Regression typical symptoms was also better (p <0.001) in patients undergoing surgery.

References

Pearson, J.P., Parikh, S., Orlando, R.C., Johnston, N., Allen, J., Tinling, S.P., & Johnston, N. (2011). Review article: reflux and its consequences – the laryngeal, pulmonary and oesophageal manifestations. Aliment Pharmacol. Ther; Conference held in conjunction with the 9th International Symposium on Human Pepsin (ISHP); Kingston-upon-Hull, UK. 21–23 April 2010. Aliment. Pharmacol. Ther., 33, 1-71.

Ovsiannikov, E.S., & Semenkova, G.G. (2004). Gastroezofagealnaya reflyuksnaya bolezn kak prichina khronicheskogo kashlya [Gastroesophageal reflux disease as the cause of chronic cough]. Cosilium Medicum, 6 [in Russian].

Ryan, D. Madanick (2013). Management of GERD-related chronic cough. Gastroenterol. Hepatol., 9 (5), 311-313.

Kollarik, M., & Brozmanova, M. (2009). Cough and gastroesophageal reflux: insights from animal models. Pulm. Pharmacol. Ther., 22 (2), 130-134.

De Giorgi, F., Savarese, M.F., Atteo, Е., Leone, C.A., & Cuomo, R. (2006). Medical treatment of gastro-oesophageal reflux disease. Acta Otorhinolaryngol. Ital., 26 (5), 276-280.

Ozaydin, I., Annakkaya Ali Nihat, Ozaydin, C., & Metin, Aydın (2014). Effects of cruroraphy and laparoscopic Nissen fundoplication procedures on pulmonary function tests in gastroesophageal reflux patients. Int. J. Clin. Exp. Med., 7 (2), 431-434.

Grubnik, V.V., & Malinovskiy, A.V. (2015). Kriticheskie aspekty laparoskopicheskoy khirurgii gastroezofagelnoy reflyuksnoy bolezni i gryzh pishchevodnogo otverstiya diafragmy [Critical aspects of laparoscopic surgery of gastroesophageal reflux disease and esophageal hiatal hernia]. Odessa: VMF-tipografiya [in Russian].

Wiener, G.J., Morgan, T.M., Copper, J.B., Castell, D.O., Sinclair, J.W., & Richter, J.E. (1988). Ambulatory 24 hour esophageal pH monitoring. Reproducibility and variability of pH parameters. Dig. Dis. Sci., 33 (9), 1127-1133.

Velanovich, V. (1998). Comparison of generic (SF-36) vs. Diseasespecific (GERD-HRQL) quality-of-life scales for gastroesophageal reflux disease. J. of Gastrointestinal Surgery, 2 (2), 141-145.

Grubnik, V.V., Malinovskiy, A.V., & Grubnik, V.V. (2016). Ispolzovanie samofiksiruyushchikh setok Progrip pri laparoskopicheskoy plastike gryzh pishchevodnogo otverstiya diafragmy [The use of self-gripping Progrip mesh during laparoscopic hiatal hernia repair]. Ukr. zhurn. maloinvazyv. ta endoskop. Khirurhii – Ukrainian Journal of Small-invasive and Endoscopic Surgery, 20 (3), 38 [in Russian].

Oshima T., & Miwa H. (2007). Pathogenesis of gastro-esophageal reflux disease. Nihon Rinsho, 65 (5), 797-801.

De Giorgi, F., Palmiero, M., Esposito, I., Mosca, F., & Cuomo, R. (2006). Pathophysiology of gastro-esophageal reflux disease. Acta. Otorhinolaryngol. Ital., 26 (5), 241-246.

Frantzides, С.T., Madan, A.K., & Carlson, M.A. (2002) Aprospective, randomized trial of laparoscopic polytetrafluoroethylene (PTFE) patch repair vs simple cruroplasty for large hiatal hernia. Stavropoulos Archives of Surgery, 137 (6), 649-652.

Furnee, E., & Hazebroek, E. (2013). Mesh in laparoscopic large hiatal hernia repair: a systematic review of the literature. Surgical Endoscopy, 27 (11), 3998-4008.

Downloads

Published

2017-07-14

How to Cite

Paranyak, M. R., & Grubnik, V. V. (2017). The effectiveness of surgical treatment of patients with respiratory symptoms of gastroesophageal reflux disease. Hospital Surgery. Journal Named by L.Ya. Kovalchuk, (2), 37–42. https://doi.org/10.11603/2414-4533.2017.2.7718

Issue

No. 2 (2017)

Section

ORIGINAL INVESTIGATIONS

License

Authors who publish their work in Hospital Surgery. Journal by L. Ya. Kovalchuk agree to the following terms:

  1. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.  
  2. Лицензия Creative Commons
  3. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.
  4. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access)