ASSESSMENT OF THE RELEVANCE OF COMORBIDITY FACTORS IN DETERMINING THE RISK OF FAILURE OF PRIMARY ARTERIOVENOUS FISTULA FORMATION
DOI:
https://doi.org/10.11603/2414-4533.2026.1.16066Keywords:
arteriovenous fistula, chronic kidney disease (CKD) 5, hemodialysis, vascular accessAbstract
The aim of the work: to assess the possibility and degree of influence of existing diseases on the risk of failure of primary distal arteriovenous fistula formation.
Materials and Methods. For assessment of failure in the formation of arteriovenous fistula, its inability to provide flow for program hemodialysis or cessation of blood flow through the arteriovenous anastomosis for a period of up to three months was considered. The study sample used data from 92 patients who had an arteriovenous fistula formed in the Volyn Regional Clinical Hospital, Department of Organ Transplantation, Liver and Pancreatic Surgery. Failure in the formation of primary arteriovenous fistula was detected in 22 patients (23.9 %).
Results. The presence of diabetes mellitus had a statistically highly significant effect on the increase in the risk of failure of AVF formation (p=0.0006), while the presence of congenital malformations of the genitourinary system had an unacceptable significance index (p=0.08). The influence of polycystic liver and kidney disease was statistically significant (p=0.0025) as well as rheumatological diseases (p=0.0061), while the influence of glomerular diseases and oncological pathology was quite questionable (p=0.012 and p=0.023, respectively).
Conclusions. Diseases may affect the risk of failure in the formation of primary native distal AVF. The presence of comorbidity does not increase the risk of failure of primary distal AVF formation. A larger study is needed to accurately assess the impact of certain diseases in combination with anatomical and physiological features on the effectiveness of AVF formation.
Received: 10.10.2025 | Revised: 05.01.2026 | Accepted: 20.02.2026
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