PORTAL VEIN EMBOLIZATION AS PREOPERATIVE MODALITY FOR PATIENTS WITH INTRAHEPATIC CHOLANGIOCARCINOMA
DOI:
https://doi.org/10.11603/2414-4533.2024.1.14647Keywords:
intrahepatic cholangiocarcinoma, liver resection, portal vein embolizationAbstract
The aim of the work: to evaluate the short-term outcomes of surgical treatment of patients with ICC after performing PVE at the preoperative stage.
Materials and methods. 84 patients with ICC underwent radical surgery from 2004 to 2018, in the Department of Liver transplantation and surgery of the State University “National Scientific Center of Surgery and Transplantology named after O.O. Shalimov” of the State institute “Shalimov’s National Scientific Center of Surgery and Transplantation” of the National Academy of Medical Sciences of Ukraine. The main group consisted of 21 (25 %) patients who underwent PVE as a preoperative preparation, and the control group – 63 (75 %) patients whom PVE was not performed.
Results and Discussion. During the 90-day period, clinically significant postoperative complications (grade IIIa–IV according to the Clavien–Dindo classification) were observed in 6 (28.5 %) cases among patients of the main group and 13 (20.6 %) cases among patients of the control group (р= 0.002). Clinically significant postoperative liver failure according to ISGLS criteria occurred in 5 (23.8 %) patients of the main group and 12 (19 %) patients of the control group (p=0.305). Reoperation was performed in 1 (4.7 %) case in the main group and in 7 (11.1 %) cases in the control group. Postoperative mortality was 3.1 % – 2 patients of the control group, while among the patients of the main group, postoperative mortality was not noted.
PVE as a method of preoperative preparation is able to provide satisfactory indicators of postoperative complications against the background of extensive liver resections both in isolation and simultaneously with vasculobiliary interventions.
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