Oxygen balance in patients with peritoneal sepsis
DOI:
https://doi.org/10.11603/2414-4533.2023.2.13840Keywords:
oxygen balance, peritoneal sepsis, hemodynamicsAbstract
The aim of the work: to investigate the peculiarities of oxygen balance disorders in peritoneal sepsis.
Materials and Methods. The study included 101 patients with peritoneal sepsis who were treated in the intensive care unit of the Ternopil Regional Clinical Hospital for the period 2017–2022. Peripheral blood parameters (hemoglobin, methemoglobin, hematocrit – generally by laboratory methods), blood gases (saturation, oxygen content and its tension in arterial and venous blood – ap.. “EasyStat”), hemodynamics (blood pressure – systolic, diastolic, pulse) were studied and average; central venous pressure; total peripheral vascular resistance), oxygen transport function of the blood; tissue metabolism (main and energy metabolism, indicators of tissue respiration – according to generally accepted formulas) and the level of lactic acid [5].
Results and Discussion. In patients with peritoneal sepsis, the following features of the oxygen balance were revealed: a certain increase in the supply of oxygen to the arterial blood by (2.8±0.2) % against the background of a high degree of hemic hypoxia (10.3±0.6) %, caused by the formation of methemoglobin and development of the degree of inactivation hypoxia (5.8±0.8) % and anemia (4.5±0.6) %. Activation of the hemodynamics system was detected: the degree of circulatory hypoxia was (-31.4±2.2) % to ensure the supply of oxygen to the tissues, which showed an intensive increase in metabolism. The tissue respiration index was (124.0±3.1) %.
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