The role and problems of post-mortem donations
DOI:
https://doi.org/10.11603/2414-4533.2022.4.13618Keywords:
organ donation, explantation, brain death, organ transplantationAbstract
The aim of the work : to determine the dependence of the number of organ explantations in effective post-mortem donors on age and laboratory results and to study the proportion of organs suitable for transplantation in the latter.
Materials and Methods. The study included 14 post-mortem donors who underwent organ explantation from May 2021 to December 2021 at the KNP KOCL, of which 56.3 % were men and 43.7 % were women. By age, the patients were divided into 2 groups: group 1 – under 50 years old, group 2–50 years and older.
Results and Discussion. According to the results of statistical processing of data, it can be argued that the groups did not differ significantly for the article, body mass index, duration of stay in HRIT, and such laboratory parameters as the average level of creatinine, sodium, ALT and AST, at the same time there was a significant difference in the content of urea and directly after age, p = 0.03 and p = 0.000034, respectively. There was no significant statistical difference in the number of explantations.
The modern development of transplantation in our country has made it possible to significantly improve the results in the fight for the lives of patients. Posthumous donation saves the life of at least 4 people at the same time. In Ukraine, there are no criteria for marginal donation, extended criteria for donation, and there is no unified protocol for conditioning a potential donor. The age of the post-mortem donor is not a critical criterion for organ donation. Despite laboratory indicators of donor safety, some organs are not suitable for further transplantation; in this study, these are 36 % of hearts, 43 % of livers and 7 % of kidneys. Follow-up studies in a larger cohort of patients are needed to further explore the effectiveness of donor use and post-transplant long-term outcomes.
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