Treatment effectiveness evaluation in patients with perilymphatic fistulas

Authors

  • O. V. Sherbul A. I. Kolomiychenko Institute of Otolaryngology of the National Academy of Medical Sciences of Ukraine
  • I. A. Srebniak A. I. Kolomiychenko Institute of Otolaryngology of the National Academy of Medical Sciences of Ukraine
  • O. M. Borysenko A. I. Kolomiychenko Institute of Otolaryngology of the National Academy of Medical Sciences of Ukraine
  • T. O. Shevchenko A. I. Kolomiychenko Institute of Otolaryngology of the National Academy of Medical Sciences of Ukraine

DOI:

https://doi.org/10.11603/2414-4533.2021.1.12027

Keywords:

microtympanotomy, perilymphatic fistula, idiopatic sensorineural hearing loss, bone conduction, cholesteatoma, air conduction, air-bone gap

Abstract

The aim of the work: to evaluate the effectiveness of treatment in patients with spontaneous and acquired PLF with chronic suppurative otitis media and cholesteatoma by studying the clinical and audiological results after microsurgical treatment with optimal combined visualization of affected area.

Materials and Methods. 33 patients with different PLF etiology aged 20 to 62 were observed in ear microsurgery and otoneurosurgery department. Patients were divided into two groups of studies depending on the PLF etiology. Group I included patients with spontaneous PLF (n=13), group II – patients with chronic suppurative otitis media with cholesteatoma and acquired PLF (n=20).

All patients were examined by: otomicroscopy, pure tone audiogram, impedancemetry, computed tomography of the temporal bones (СT) and magnetic resonance image (MRI) of the brain.

All the results were assessed before and after drug treatment and 6 months after surgical treatment. Classification of hearing impairment grades by World Health Organization (WHO) were used.

All patients had undergone microtympanotomy under microscopic and endoscopic visualization of PLF region followed by its closure with plugging material.

The software used for statistical analysis were MSExсel 2010 and Statistica-8.0. All statistical analyses were considered significant where the p value was less than 0.05.

 Results and Discussion. In both groups bone threshold decrease of all of the above frequencies was observed 6 months after surgery

In patients of group I before surgery bone threshold was 29.2 dB to 58.8 dB while in patients of group II – between 6.3 dB to 25.0 dB.

6 months after surgery tendency to decrease the bony threshold was observed in both groups, whereas in patients of group II – significant decrease of all of the above thresholds from 4.5 to 21.8 dB.

Decrease of the air threshold was defined in both groups, with more significant values on 500 Hz to 1kHz in patients from group II with a tendency to decrease of all above mentioned frequencies in patents from group I.

A significant reduction of air-bone gap in patients from both groups 6 months after operative treatment were found. These data suggest functional effectiveness of microtympanotomy with PLF sealing using combined endoscopic and microscopic assistance.

References

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Published

2021-04-30

How to Cite

Sherbul, O. V., Srebniak, I. A., Borysenko, O. M., & Shevchenko, T. O. (2021). Treatment effectiveness evaluation in patients with perilymphatic fistulas . Hospital Surgery. Journal Named by L.Ya. Kovalchuk, (1), 82–89. https://doi.org/10.11603/2414-4533.2021.1.12027

Issue

No. 1 (2021)

Section

EXPERIENCE OF WORK

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