RHEOLOGICAL STUDY OF NATURAL ZEOLITE PASTE WITH SILICA DIOXIDE

Authors

  • V. D. Rybachuk National University of Pharmacy, Kharkiv
  • O. A. Ruban National University of Pharmacy, Kharkiv

DOI:

https://doi.org/10.11603/2312-0967.2018.1.8598

Keywords:

rheological properties, natural zeolite, clinoptilolite, silica dioxide, paste.

Abstract

The aim of the work. Studying the rheological properties of natural zeolite (clinoptilolite) paste with silica dioxide as a thickener, to select their optimal concentrations.

Materials and Methods. The objects of the study were model compositions of pastes containing natural zeolite powder (clinoptilolite) in the concentrations of 15 %, 20 %, 25 % and 30 % as the active ingredient, and silica dioxide as a thickener in the concentrations of 5.0 %, 6.0 %, 7.0 % and 8.0 %. Determination of the rheological parameters was carried out at a temperature of 20 ± 2 °C using a MYR VR3000 (Spain) viscometer based on the Brookfield method, studies were carried out in the shear range from 1 s-1 to 200 s-1 using coaxial cylinders.

Results and Discussion. It is determined that the samples under investigation are related to thixotropic-structured pseudoplastic systems with a coagulation-type structure. Natural zeolite (clinoptilolite) along with silica dioxide has a structuring effect on the dispersed system, and their optimal concentrations, providing sufficient structure formation, are 25–30 % and 7–8 % respectively.

Conclusion. The rheological properties of natural zeolite paste (clinoptilolite) with silica dioxide, as a thickening agent, have been studied, and their optimal structure-forming concentrations have been chosen. The results obtained will be used to develop the composition of paste-enterosorbents with natural zeolite.

Author Biographies

V. D. Rybachuk, National University of Pharmacy, Kharkiv

Candidate of Pharmacy (Ph.D), associate professor of the Department of industrial technology of drugs, National University of Pharmacy.

O. A. Ruban, National University of Pharmacy, Kharkiv

Doctor of Pharmacy (Dr. habil), head of the Department of industrial technology of drugs, National University of Pharmacy.

References

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Published

2018-03-24

How to Cite

Rybachuk, V. D., & Ruban, O. A. (2018). RHEOLOGICAL STUDY OF NATURAL ZEOLITE PASTE WITH SILICA DIOXIDE. Pharmaceutical Review Farmacevtičnij časopis, (1), 23–28. https://doi.org/10.11603/2312-0967.2018.1.8598

Issue

No. 1 (2018)

Section

Pharmaceutical technology, biopharmacy, homeopathy, biotechnology

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