PUBLICATION ACTIVITY ON THE SEARCH FOR NOVEL BIOLOGICALLY ACTIVE COMPOUNDS OF SYNTHETIC ORIGIN IN UKRAINIAN SCHOLARLY JOURNALS: A RETROSPECTIVE SCIENTOMETRIC ANALYSIS
DOI:
https://doi.org/10.11603/2312-0967.2025.3.15583Keywords:
science of science, scientometrics, publication activity, novel biologically active compounds of synthetic origin, medicine, in silico research, pharmacological/biological screening, inter-institutional collaborationAbstract
The aim of this work is to develop a profile of publications on the search for novel biologically active compounds of synthetic origin, published in Ukrainian scholarly journals during 2019–2024, in order to identify the dynamics of publication activity, structural patterns, leading research institutions, and thematic dominants.
Materials and Methods. A total of 32 journals, which are included in the List of Scientific Professional Publications of Ukraine, were reviewed. The sample comprises articles thematically related to the search for novel biologically active compounds of synthetic origin and affiliated with Ukrainian research institutions. Scientometric methods (statistical analysis, counting the number of publications, content analysis, and thesaurus analysis) and generalization were used.
Results and Discussion. It was established that 172 articles on the search for novel biologically active compounds of synthetic origin were published across 15 journals (accounting for 46.9% of the total number). Publication activity showed a decline from 2019 to 2022, a sharp drop in 2022, and a gradual increase in 2023–2024. Five journals accounted for 79.1% of the publications, with the «Journal of Organic and Pharmaceutical Chemistry» being the leader (26.7%). The publications represented 63 institutions, with a total participation index of 309, which indicates active inter-institutional collaboration. The thematic analysis revealed a dominance of research areas such as chemical synthesis (32.6%), computational chemistry methods (28.5%), and pharmacological/biological screening (18.6%).
Conclusions. The study demonstrates the existence of a stable research paradigm in the search for novel biologically active compounds of synthetic origin, with the potential for integrating comprehensive approaches. This integration may contribute to enhancing the international visibility of Ukrainian research.
References
Cherednyk LA. Naukometriia yak haluz naukoznavstva ta navchalna dystsyplina [Scientometrics as a branch of science of science and a teaching discipline]. In: Informatsiia ta Sotsium: materialy VI Mizhnar nauk-prak konf; 2021 Jun 4; Vinnytsia, Ukraine. Vinnytsia: DonNU imeni Vasylia Stusa; 2021. p. 67–69. [Internet]. Available from: https://jias.donnu.edu.ua/article/view/11454 (accessed 2025-09-30). Ukrainian.
Didenko YV, Radchenko AI. Publikatsiina aktyvnist yak sposib naukovoi komunikatsii ta honytvy za reitynhamy [Publication activity as a way of scientific communication and racing for rankings]. Visn Nac Akad Nauk Ukr. 2017;(9):82–98. DOI:10.15407/visn2017.09.082. Ukrainian. DOI: https://doi.org/10.15407/visn2017.09.082
Paska O, Kremin Yu, Hromovyk B, Lesyk R. Dosvid vprovadzhennia prozoroi systemy otsiniuvannia rezultativ diialnosti naukovtsiv [Experience in implementing a transparent system for evaluating researchers’ performance]. Visnyk Natsionalnoi akademii pedahohichnykh nauk Ukrainy / Herald Natl Acad Educ Sci Ukr. 2023; 5(1):1–12. DOI:10.37472/v.naes.2023.5115. Ukrainian. DOI: https://doi.org/10.37472/v.naes.2023.5115
Naheem KT, Sivaraman P, Saravanan G. A Scientometric Analysis of Global Literature. Qualitative and Quantitative Methods in Libraries. 2022; 11 (3): 455-471. URL: https://www.qqml-journal.net/index.php/qqml/article/view/770/683.
Zoukh I, Tabet M, Awaisu A. Scientometric analysis of research productivity in clinical pharmacy and practice: a 12-year review at a Middle Eastern university. J Pharm Policy Pract. 2025. Mar 27;18(1):2480154. DOI: 10.1080/20523211.2025.2480154. DOI: https://doi.org/10.1080/20523211.2025.2480154
Adam KM, Ali EW, Elangeeb ME, Abuagla HA, Elamin BK, Ahmed EM, Edris AM, Ahmed AAEM, Eltieb EI. Intelligent Care: A Scientometric Analysis of Artificial Intelligence in Precision Medicine. Med Sci (Basel). 2025 Apr 19;13(2):44. DOI: 10.3390/medsci13020044. DOI: https://doi.org/10.3390/medsci13020044
Osadcha AB. Porivniannia rivnia publikatsiinoi diialnosti u sferi medytsyny v Ukraini ta krainakh svitu [Comparison of publication activity in medicine in Ukraine and worldwide]. Nauka Tekhnol Innov. 2020;2(14):74–83. DOI: 10.35668/2520-6524-2020-2-09. Ukrainian. DOI: https://doi.org/10.35668/2520-6524-2020-2-09
Savina RV, Voloshchuk OV, Korkach VS, Melchenko YV. Naukometrychnyi analiz publikatsiinoi aktyvnosti fakhivtsiv DU “Instytut hromadskoho zdorovia im. O.M. Marzieieva NAMN Ukrainy” u vydanniakh, shcho vkhodiat do mizhnarodnykh baz danykh [Scientometric analysis of publication activity of specialists of the O.M. Marzieiev Institute of Public Health, NAMS of Ukraine, in journals indexed in international databases]. Dovkillia Zdorov. 2017; (2):66–70. [Internet]. Available from: http://nbuv.gov.ua/UJRN/dtz_2017_2_16 (accessed 2025-09-30). Ukrainian.
Tronko MD, Paster IP. Naukometrychnyi analiz publikatsiinoi aktyvnosti naukovtsiv DU “Instytut endokrynolohii ta obminu rechovyn im. V.P. Komisarenka NAMN Ukrainy” za danymy bazy Google Scholar [Scientometric analysis of publication activity of scientists of the State Institution "V. P. Komisarenko Institute of Endocrinology and Metabolism of the National Academy of Medical Sciences of Ukraine" according to the scientometric database Google Scholar]. Endokrynol. 2019;24(1):46–52. [Internet]. Available from: http://nbuv.gov.ua/UJRN/enkrl_2019_24_1_10 (accessed 2025-09-30). Ukrainian.
Kocyigit BF. Scopus-based bibliometric analysis of publication activity in the field of healthy aging in 2013–2022. Anti-Aging East Eur. 2023;2(2):70-5. DOI:10.56543/aaeeu.2023.2.2.01. DOI: https://doi.org/10.56543/aaeeu.2023.2.2.01
Mukhamediyarov M, Bekaryssova D. Publication activity trends in the field of social media in rheumatology: a Web of Science-based bibliometric analysis. Rheumatol Int. 2025;45(5):119. DOI:10.1007/s00296-025-05867-7. DOI: https://doi.org/10.1007/s00296-025-05867-7
Miller C, Dejaco A, Gumz N, Nemeth M. The pediatric anesthesiology publication activity and landscape over the past two decades: a longitudinal scientometric analysis. Paediatr Anaesth. 2024;34(3):243–250. DOI:10.1111/pan.14811. DOI: https://doi.org/10.1111/pan.14811
Vladsimirska OV, Hrom OL, Hromovyk BP, Horishnyi VYa, Bohosta MS. Naukoznavchyi analiz kandydatskykh dysertatsii, vykonanykh pid kerivnytstvom profesora M.M. Turkevycha [Scientometric analysis of PhD theses supervised by Prof. M.M. Turkevych]. Farm Zh. 1995; (3):41–45. [Internet]. Available from: https://pharmj.org.ua/archives/1995/1995-3.pdf (accessed 2025-09-30). Ukrainian.
Kissin I. Scientometrics of drug discovery efforts: pain-related molecular targets. Drug Des Devel Ther. 2015 Jul 1;9:3393-404. DOI: 10.2147/DDDT.S85633. DOI: https://doi.org/10.2147/DDDT.S85633
Sankaralingam, R., Surulinathi, M. and Srinivasaragavan, S. (2020). Indian contribution to Drugs Discovery: A Scientometric Mapping of Publications, Gedrag and Organisatie Review, 2020, 33(3), 712-734. DOI: 10.37896/GOR33.03/462. DOI: https://doi.org/10.37896/GOR33.03/462
Kormshchykova S. Naukometrychni doslidzhennia v informatsiinykh tekhnolohiiakh [Scientometric research in information technology]. Materialy XLVII nauk.-tekhn. konf. pidrozdiliv VNTU. Vinnytsia, 2018. [Internet]. Available from: https://conferences.vntu.edu.ua/index.php/all-fm/all-fm-2018/paper/view/4239 (accessed 2025-09-30). Ukrainian.
Tsymbaliuk OV, Hromovyk BP. Informatsiini potreby naukovtsiv u sferi farmatsevtychnoi/medychnoi khimii: naukoznavcha kharakterystyka [Information needs of researchers in pharmaceutical/medicinal chemistry: a scientometric profile]. Farm Chasop. 2025; 2:32–39. DOI:10.11603/2312-0967.2025.2.15436. Ukrainian. DOI: https://doi.org/10.11603/2312-0967.2025.2.15436
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Pharmaceutical Review / Farmacevtičnij časopis
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
The authors who publish their materials in this journal agree with the following terms:
- Authors reserve the right to authorship of their work and assign to the journal the right to first publish this work under the terms of the Creative Commons Attribution License, which allows other persons to freely distribute the published work with a mandatory reference to the authors of original work and the first publication of work in this journal
. - Authors have the right to make independent extra-exclusive work agreements in the form they are published by this journal (for example, posting work in an electronic repository of an institution or publishing as part of a monograph), provided that the link to the first publication of the work in this journal is maintained.
Journal policy allows and encourages publication of manuscripts on the Internet (for example, in institutions repositories or on personal websites), both before the publication of this manuscript and during its editorial review, as it contributes to productive scientific discussion and positively affects the efficiency and dynamics of the citation of the published work (see The Effect of Open Access).
