ANALYSIS OF EXTRACTION METHODS AND THE PROSPECTS OF THEIR IMPLEMENTATION IN THE LIFE CYCLE OF HERBAL MEDICINAL PRODUCTS
DOI:
https://doi.org/10.11603/2312-0967.2025.3.15549Keywords:
extraction, herbal substance, preparation, technology, technological process, medicinal productAbstract
The aim of the work is to study and analyze available methods of extraction of herbal raw materials; to assess their advantages and disadvantages in terms of implementation in the development and production of herbal preparations as active pharmaceutical ingredients of medicinal products.
Materials and Methods. The bibliosemantic method was used during the research. The scientific publications in professional editions were used as materials.
Results and Discussion. Extraction methods can be divided into two groups: conventional and novel. Conventional extraction methods are based on classical methods of isolating certain groups of biologically active substances using solvents of different polarity as extractants. Novel methods are based on innovative approaches that ensure a high yield of extractive substances in a relatively short process time, combined with the absence or low need for organic solvents. An important criterion for choosing a method and its subsequent effectiveness are the physicochemical properties of phytochemical compounds.
Conclusions. The available methods of extraction of herbal raw materials have been analyzed from the point of view of their application at the development stages and the prospects of scaling up to production. It has been established that both conventional and novel extraction methods have advantages and disadvantages inherent to each method. It has been found that from scaling up point of view conventional methods look more acceptable based on their technological flexibility and economic feasibility. It has been noted that a promising direction is the implementation of combinations of novel and conventional extraction methods in the life cycle of products. The further stage of research should be the practical application of a combination of extraction methods in the development of active pharmaceutical ingredients and medicinal products based on them.
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