PHARMACEUTICAL CARE FOR PERSONES WITH MIGRAINE: WAYS TO IMPROVE THE EFFICACY AND SAFETY OF THERAPY

Authors

DOI:

https://doi.org/10.11603/2312-0967.2025.1.15170

Keywords:

migraine, pharmaceutical care, nonprescription and prescription medicines, efficacy and safety of the therapy

Abstract

The aim of the work. Identify the role of the patient/pharmacy visitor, physician/pharmacist in the implementation of pharmaceutical care in the treatment of migraine.

Materials and Methods. The methodological basis of the study is based on the principles of objectivity and systematicity. The study used a set of general scientific and special methods: theoretical, method of generalization, data systematization, comparison, analysis, and questionnaire. A questionnaire survey was conducted among 20 pharmacy visitors who visited the pharmacy to purchase a drug for the treatment of migraine.

Results and Discussion. For mild to moderate attacks, our respondents used simple analgesics and NSAIDs (ibuprofen, paracetamol, naproxen, and acetylsalicylic acid). The choice of medications for symptomatic treatment was based on the principles of responsible self-medication with the advisory participation of a pharmacist. For severe seizures, triptans were used: sumatriptan, zolmitriptan, and risatriptan, which were prescribed by a doctor. Out of 20 respondents, only 3 received preventive treatment, which is 15%. The medications used by respondents for preventive treatment were: propranolol (10 mg tablets); metoprolol (25 mg film-coated slow-release tablets) and topiramate (25 mg film-coated tablets). As for dosage forms, the most popular were tablets and capsules. The majority of respondents (90%) preferred them when choosing a dosage form. Only 2 respondents (10%) preferred nasal spray. Regarding the rules for taking medications for migraine treatment/prevention: 16 respondents (80%) adhere to the rules of taking medications, and only 4 respondents (20%) did not attach due importance to the conditions of rational use of medications. Among the factors influencing treatment adherence, respondents mentioned: convenient dosage form, rapid onset of action, effect duration, minimal need for repeat dose, and the possibility of self-medication.

Conclusions. Pharmaceutical care (at all stages of its implementation) plays an important role in improving the efficacy and safety of migraine therapy. It is the interaction of medical and pharmaceutical professionals and a high degree of involvement of persons with migraine in the process that will help prevent attacks, reduce the frequency and severity of headaches, and improve quality of life. Improvement of pharmaceutical care in the treatment of migraine should be continuous, taking into account the latest medical technologies and the development of knowledge in neurology.

Author Biographies

T. S. Sakharova, Odesa I. I. Mechnikov National University

DSс (Pharmacy), professor of the Department of General and Clinical Pharmacy

I. A. Otrishko, National University of Pharmacy of the Ministry of Health of Ukraine

PhD (Pharmacy), Associate Professor of the Department of Pharmacology and Clinical Pharmacy

К. V. Vietrova, National University of Pharmacy of the Ministry of Health of Ukraine

PhD (Pharmacy), associate professor of the Department of Pharmacology and Clinical Pharmacy

N. P. Bezugla, PE Private Production Company «Acinus», Kropyvnytskyi

PhD (Medicine), associate professor, doctor

T. S. Zhulai, Municipal Clinical Hospital No. 30 of the Kharkiv City Council

PhD (Medicine), associate professor, doctor

V. V. Pidhaina, National University of Pharmacy of the Ministry of Health of Ukraine

PhD (Pharmacy), Assistant Professor of the Department of Pharmacology and Clinical Pharmacy

О. О. Kostina, National University of Pharmacy of the Ministry of Health of Ukraine

M (Pharmacy), pharmacist

References

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Published

2025-03-31

How to Cite

Sakharova, T. S., Otrishko, I. A., Vietrova К. V., Bezugla, N. P., Zhulai, T. S., Pidhaina, V. V., & Kostina О. О. (2025). PHARMACEUTICAL CARE FOR PERSONES WITH MIGRAINE: WAYS TO IMPROVE THE EFFICACY AND SAFETY OF THERAPY. Pharmaceutical Review Farmacevtičnij časopis, (1), 113–122. https://doi.org/10.11603/2312-0967.2025.1.15170

Issue

Section

Pharmaceutical care