PELARGONIUM SIDOIDES, HEDERA HIBERNICA AND ORIGANUM VULGARE IN THE PHARMACEUTICAL PREPARATIONS PRESENTED ON THE MARKETS OF UKRAINE AND POLAND
DOI:
https://doi.org/10.11603/2312-0967.2021.3.12395Keywords:
pelargonium roots Pelargonium Sidoides, oregano herba Origani vulgare, ivy leaves Hedera hibernica, herbal preparations, pharmaceutical market of Ukraine, pharmaceutical market of PolandAbstract
The aim of the work. Analyze the range of drugs from the pharmaceutical markets of Ukraine and Poland, which contain substances of pelargonium root (Pelargonium Sidoides), oregano (Origanum vulgare) and ivy leaves (Hedera Hibernica). Based on the obtained results to determine the feasibility of developing a new multicomponent drug with their content.
Materials and Methods. The analysis of pharmaceutical markets was performed according to the data of the State Register of Medicinal Products of Ukraine and Poland (as of July 2021). The work is performed using logical systematizing, generalizing and graphical methods.
Results and Discussion. Most of the analyzed products of the pharmaceutical markets of Ukraine and Poland with the content of pelargonium stonecrop, oregano, ivy are presented in the form of syrups. These are mainly single-component medicines (73,33% in Ukraine and 91.7% in Poland). In both countries, the largest percentage of the studied drugs are produced by domestic pharmaceutical companies, in second place drugs are imported from Germany. The most common drugs containing Origanum vulgare, Hedera Hibernica, Pelargonium Sidoides are drugs used for coughs and colds (78.21%).
Conclusions. The development of a new multicomponent drug containing oregano, ivy leaves and pelargonium is promising because there are no analogues of such a drug in the domestic pharmaceutical market.
References
Incidence of influenza and SARS in Ukraine [Internet]. Public Health Center of Ukraine [cited 2021 July 20] Available from: URL: https://phc.org.ua/kontrol-zakhvoryuvan/inshi-infekciyni-zakhvoryuvannya/monitoring-i-ocinka/zakhvoryuvanist-na-grip-ta-grvi-v-ukra
Hudzenko AV, Tsurkan OO, Kovalchuk TV. [Domestic market of multicomponent herbal medicines: analysis of the state structure and prospects of development]. Farmatsevtychnyi zhurnal. 2012;1: 8-12. Available from: URL: http://nbuv.gov.ua/UJRN/pharmazh_2012_1_3.
Kvashnina LV, Chernyshov VP, Matviienko IM, Ihnatova TB, Osypchuk DV. [The effect of the drug Resistol® on the humoral and cellular immunity of children with recurrent and acute viral respiratory diseases: the results of the study]. Sovremennaia pedyatryia. 2018;8: 104-113.
Pavliuk IV, Stadnytska NYe, Yasitska-Misiak I, Vechorek P, Zahorii HV, Brezvyn OM, Novikov VP. [Study of the biological activity of the secondary extract from the meal of oregano (Origanum vulgare)]. Ukrainskyi biofarmatsevtychnyi zhurnal. 2015;1: 21-24.
Yousefian Z, Golkar P, Mirjalili MH. Production Enhancement of medicinally active coumarin and phenolic compounds in hairy root cultures of Pelargonium sidoides: the effect of elicitation and sucrose. Journal of Plant Growth Regulation. 2021;40(2): 628-641.
Widyastuti PA, et al. Phytochemicals and Antioxidant Activities Evaluation of Origanum vulgare (L.) Stem Bark Extracts. Pharmacognosy Journal. 2021;13.4. DOI:10.5530/pj.2021.13.124
Torre MP, Vizmanos JL, Cavero RY, Calvo MI. Improvement of antioxidant activity of oregano (Origanum vulgare L.) with an oral pharmaceutical form. Biomedicine & Pharmacotherapy, 2020;129: 110424.
Fazio S, et al. Tolerance, safety and efficacy of Hedera helix extract in inflammatory bronchial diseases under clinical practice conditions: a prospective, open, multicentre postmarketing study in 9657 patients. Phytomedicine. 2009;16.1: 17-24. DOI https://doi.org/10.1016/j.phymed.2006.05.003
Zazharskyi VV, et al. Antibacterial and fungicidal activities of ethanol extracts from Cotinus coggygria, Rhus typhina, R. trilobata, Toxicodendron orientale, Hedera helix, Aralia elata, Leptopus chinensis and Mahonia aquifolium. Regulatory Mechanisms in Biosystems. 2020;11.2: 305-309. https://doi.org/10.15421/022046
Song JH, et al. Antiviral activity of hederasaponin B from hedera helix against enterovirus 71 subgenotypes C3 and C4a." Biomolecules & Therapeutics 2014;22.1(41): 108 DOI doi: 10.4062/biomolther.2013.
Search for medicines [Internet]. Website of the State Registration of Medicines of Ukraine. [cited 2021 July 20] Available from: URL: http://www.drlz.com.ua/
Search for medicines [Internet]. The site of the register of medical drugs of Poland URL:http://pub.rejestrymedyczne.csioz.gov.pl/
ATC-classification [Internet]. Compendium is a directory of medicines in Ukraine [cited 2021 July 20] Available from: URL:https://compendium.com.ua/uk/atc/
Law of Ukraine "On Medicinal Products. URL: https://rav.com.ua/useful_know/norm_baza/zakon/law_medical_products/
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