MODERN ANALYTICAL APPROACHES TO THE DETECTION OF COUNTERFEIT MEDICINES
DOI:
https://doi.org/10.11603/2312-0967.2020.2.11182Keywords:
falsification of medicines, visual control, analytical methods of control, counteraction, detection, wholesale and retail sale of medicines, quality and safety of medicinesAbstract
The aim of the work. To analyze modern analytical technologies for detection of counterfeit drugs and to substantiate scientific and practical approaches to their use during wholesale and retail sales of medicines.
Materials and Methods. Data from domestic and foreign sources on modern analytical methods of control of medicines, domestic regulations in the field of control of medicines, analytical methods of pharmaceutical analysis; logical, structural, comparative analysis, expert evaluation, generalization and systematization.
Results and Discussion. It is established that visual methods of detecting counterfeit drugs during quality control of medicines in pharmacies are currently ineffective. Visual assessment allows detecting only gross counterfeit drugs on the basis of external signs of packaging and the drug itself. Today's advanced level of manufacturing counterfeit medicines requires the introduction into practice of innovative drug control technologies that make it possible to distinguish counterfeit medicines from the original with a high probability. Modern analytical methods act as an effective means of rapid and reliable monitoring of the quality of drugs in their control. The article presents the essence of available in the use and maintenance of analytical methods and equipment used in drug control in economically developed countries, and can also be recommended for use in Ukraine.
Conclusions. The analysis of modern technological approaches to the detection of counterfeit drugs indicates the need to supplement the visual methods of quality control of drugs in domestic pharmacies by modern analytical methods of express analysis in order to improve the quality and safety of pharmaceutical care.
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