NOVEL METHODS OF CONTAINMENT OF SEXUALLY TRANSMITTED INFECTIONS
DOI:
https://doi.org/10.11603/1681-2727.2019.1.9933Keywords:
human immunodeficiency virus (HIV), sexually transmitted infections (STIs), prevention, biomedical technologiesAbstract
Every day, more than 1 million people are infected with sexually transmitted infections (STIs), which constitute a significant part of human morbidity and increase the risk of acquiring human immunodeficiency virus (HIV). Existing strategies for controlling and preventing STIs, including behavioral interventions, condom distribution and timely treatment, did not result in a significant reduction, indicating the need for new strategies.
The aim of this review is to synthesize new biomedical approaches to STI prevention, including multi-purpose technologies, as well as to identify the scientific and organizational obstacles that need to be addressed.
For the period from 1990 to 2018, the results of their own researches, articles found in the PubMed database, UNAIDS global reports (UNAIDS), the United Nations AIDS Action Agencies, country reports, World Health Organization (WHO) materials, were analyzed.
A systematic analysis of clinical studies of female condoms, local gel-based microbicides, vaginal rings, tablets, films and nanofibers was conducted. The state of chemical prophylaxis of genital herpes, trichomonas was analyzed. The principles of multi-purpose prevention technology (MPT) and prospects of research was presented.
Conclusion. HIV and other STIs are part of global health crises. At the present time, new MPT are being developed for protection against HIV and STIs, taking into account mechanisms of infection, cultural and social factors.
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