CLINICAL-EPIDEMIOLOGICAL AND LABORATORY FEATURES OF THE CURRENT COURSE OF ERYSIPELAS

Abstract

Despite the fact that erysipelas is a well-known infection, the incidence remains stable. The infection has a tendency to frequent relapses, which leads to the long-term incapacity of patients.

The aim of the work – to establish the peculiarities of the current course of the erysipelas and the quality of life depending on the frequency of the infection based on the study of epidemiology, clinic, the severity of endogenous intoxication, the level of reactivity of the organism.

Patients and methods. Inspection and research of medical records for 75 patients with erysipelas. Calculation of integrative indexes of endogenous intoxication and immunoreactivity. The SF-36 questionnaire was used for the assessment of the quality of life. The comparison group included 44 clinically and anamnestically healthy individuals.

Results. The patients were divided into three groups with 25 people in each: with primary, repeated, and relapsing erysipelas. Women predominated among patients (78.7 %). The age was (54.2±4.1) years. The largest number of hospitalized people was detected in July-August. The course of the infection was moderate in 90.0 % of the cases. Erythematosus predominated among the clinical forms of disease (54 patients, 72.0 %). Indexes of non-specific reactivity and inflammation activity have a tendency to decrease in case of relapsing erysipelas (p<0.05–0.001). The indicator of the psychological health component for patients with primary (43.8±0.7) points and repeated (44.6±0.9)points forms of erysipelas was 12.0 % higher than those with a relapsing form of erysipelas – (38.9±1.2) points p<0.01. The parameters of the physical component for patients with primary and repeated forms of erysipelas were on the same level (respectively, (46.1±0.5) points) and (47.4±1.0) points, p>0.05). The lowest one was for patients with relapsing form of erysipelas (42.1±1.3) points p<0.05.

Conclusions. A significant increase of the endogenous intoxication indexes and decrease of non-specific reactivity indexes were discovered in relapsing erysipelas compared to the primary erysipelas and control groups. The lowest indicators of the physical and psychological component of health were observed for patients with relapsing form of erysipelas.