CLINICAL AND EPIDEMIOLOGICAL FEATURES OF LEPTOSPIROSIS IN DIFFERENT LANDSCAPE ZONES

Abstract

The human leptospirosis in different landscape zones of Carpathian area was study. Serological verification by ELISA had been carried out and 82 cases of leptospirosis were defined during one-year investigation. Human leptospirosis had detected in all sites: 19 cases in mountain area, 25 – plain and 38 in mixed relief zones. The percentage of leptospirosis in the structure of infectious diseases was on average in plain zone (22.7±2.4) %, mountainous (18.8±2.1) %, and mixed zone – (39.2±2.5) %. The incidence case rate was high in all areas: 11.0–15.2 per 100 thousand population (plain), 6.2–39.7 per 100 thousand population (mountains), 9.7–26.8 per 100 thousand population (mixed relief).

The majority of patients – (72.7±2.5) % lived in rural areas. The proportion of male patients was higher – (65.8±4.8) % than the female only in mixed relief area. The patients were from all age groups of the population, but the adult (73.1±2.5) % had been prevailed. A number of occupational risk factors were identified that could potentiate the risk of exposure.

Predominantly leptospirosis had been manifested by mild and moderate disease with polymorphic clinical course. The clinical forms of leptospirosis with hyperthermia and defeat of the respiratory tract (41.5±5.4) % had been prevailed in all zones. Typically the classic version of the clinical manifestation and hepatitis syndrome – (14.6±3.9) % had been presented.