PHAGOCYTIC ACTIVITY OF NEUTROPHILS IN PATIENTS WITH ACUTE HEPATITIS B

Authors

  • M. M. Popov I. Mechnykov Institute of Microbiology and Immunology of the National Academy of Medical Sciences of Ukraine, Kharkiv
  • A. I. Sklyar I. Mechnykov Institute of Microbiology and Immunology of the National Academy of Medical Sciences of Ukraine, Kharkiv

DOI:

https://doi.org/10.11603/1681-2727.2017.3.8226

Keywords:

acute hepatitis B, phagocytosis, phagocytic index of neutrophils, phagocytic number of neutrophils, symbiotic.

Abstract

When penetrating inside organism infection agents meet resistance from innate immune cells, where phagocytes are the first to meet the agents.

The aim of the work –  to study the polymorph nuclear neutrophils functional state in patients’ blood for acute HBV infection in varying degrees of severity in the dynamics of conventional treatment and after prescription of  symbiotic.

Patients and methods. 108 patients with acute hepatitis B were under observation. 56 men and 52 women with an average 34±1.9 (from 18 to 69 years old). 17 healthy persons were included into a control group. In order to estimate phagocytic activity of neutrophils (PAN) phagocytic index of neutrophils (PIN) and phagocytic number of neutrophils (PNN) with incubation period of 30, 60 and 180 minutes were detected.

Conclusions. We can admit that compensatory possibilities of neutrophils are essential since they are able to maintain balance in phagocytic system in case of intensive HBV load. Including symbiotic to a regular therapy we can observe increasing of intensity of phagocytosis as well as regulation of absorbing potential of neutrophils among the patients with different serenity degrees of HBV infection.

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Published

2017-11-06

How to Cite

Popov, M. M., & Sklyar, A. I. (2017). PHAGOCYTIC ACTIVITY OF NEUTROPHILS IN PATIENTS WITH ACUTE HEPATITIS B. Infectious Diseases – Infektsiyni Khvoroby, (3), 45–51. https://doi.org/10.11603/1681-2727.2017.3.8226

Issue

No. 3 (2017)

Section

Original investigations

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