MODERN REALITIES OF HEPATITIS A IN THE TRANSCARPATHIAN REGION
DOI:
https://doi.org/10.11603/1681-2727.2017.2.7995Keywords:
hepatitis A, immunoglobulin G to hepatitis A.Abstract
The aim of the work – to establish the real prevalence of hepatitis A using the method of detecting anti-HAV IgG and the ratio of icteric forms of the diseases to erased, atypical, anicteric forms in the residents of the Transcarpathian region.
Patients and methods. Study of available anti-HAV IgG was conducted in 262 adults, patients of regional medical institutions. Targeted surveys on a history of the disease with symptoms of jaundice were conducted in 203 patients within regional clinical infectious diseases hospital.
Results. Antibody to hepatitis A was detected in 77.48 % of patients. The frequency of detection of immunoglobulin G virus depended on the age and place of residence and did not depend on sex, the lowest were aged 18 to 29 years and maximum 60 years of age or more (p<0.001); in the residents of the city Uzhgorod were significantly less than residents of other cities, villages and residents of the Transcarpathian region as a whole (p<0,01-0,001).
Conclusions. The results show a significant spread of hepatitis A among residents of the Transcarpathian region. Officially registered less than in the tenth of the patients who had the disease. Among the adult population anicteric forms of hepatitis A are dominant. The frequency of anamnestic antibodies to hepatitis depends on the age and place of residence.
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