MICROELEMENT DISTURBANCES IN CHILDREN SUFFERING FROM SHIGELLOSIS AND INFECTED WITH HELICOBACTER PYLORI
DOI:
https://doi.org/10.11603/1681-2727.2016.4.7216Keywords:
shigellosis, Helicobacter pylori, microelements, zinc, copper, children.Abstract
The article deals with the outcomes of assessment of zinc and copper content of serum in children suffering from shigellosis and infected with Helicobacter pylori. Significant disorders in the system of microelement homeostasis in acute phase of shigellosis were revealed. Zinc deficiency of blood serum, which was more pronounced in children infected with H. pylori, was estimated, as well as decreased copper levels were observed: in children without background infection it was significantly decreased, in children infected with H. pylori it was insignificantly decreased. Prior to the period of early convalescence, substantial increase of content of microelements occurs, but in children, infected with H. pylori, complete restoring of Zinc level is not observed. The data, which have been obtained, represent complicated character of restoring processes with absence of full recovery of functional features of GI tract in children infected with H. pylori, despite regression of clinical manifestations of shigellosis and can be used for further improvement of treatment provided for such category of patients.References
Milevskaya, Ye.V. (2015) Optimizatsiya lecheniya ostrykh kishechnykh infektsiy u detey. Sbornik materialov VI Mezhdunarodnoy nauchno-prakticheskoy molodezhnoy konferentsii «Nauchnyye stremleniya» / OOO «Laboratoriya intellekta» i Tsentr molodezhnykh innovatsiy, Minsk: «Entsiklopediks», 68-71.
Andreychyn, M.A. (2015) Shyhelʹoz. Zdorov'ya Ukrayiny, tematicheskiy nomer: INFEKTSII V PRAKTIKE VRACHA. Rezhym dostupu http://health-ua.com/article/1605.html.
Gorelov, A.V., Grigorovich, M.S. (2012) Ostryye kishechnyye infektsii u detey: otdalennyye iskhody, faktory ikh opredelyayushchiye. Optimizatsiya putey reabilitatsii: monografiya, M.: Kirov.
Zakordonets, L.V., Kramarev, S.A., Beregovaya, T.V., Tolstanova, A.N. (2013) Sovremennyye podkhody k lecheniyu ostroy kishechnoy infektsii u detey. Zdorov'ye rebenka, 5, 48-52.
Abaturov, A.Ye., Gerasimenko, O.N., Zavgorodnyaya, N.YU. (2014) Khronicheskiye CagA (+) Helicobacter pylori-assotsiirovannyye gastrity u detey. Khar'kov: S.A.M.
Khokhlova, Ye.A., Tarasova, L.A., Stepashina, T.Ye. (2011) Uchastiye selena i tsinka v patogeneze vospalitel'nykh zabolevaniy zheludochno-kishechnogo trakta (analiz literaturnykh dannykh). Vestnik CHGU, 3, 487-493.
Bel'mer, S.V., Gasilina, T.V. (2009) Mikroelementy pri vospalitel'nykh zabolevaniyakh zheludochno-kishechnogo trakta. Voprosy sovremennoy pediatrii, 1, 121-124.
Loboda, A.M. (2009) Míkroelementní porushennia u dítey. Sovremennaya pediatriya, 1 (23), 89-92.
Khaliullina, S.V. (2013) Klinicheskoye znacheniye defitsita tsinka v organizme rebenka (obzor literatury). Vestnik sovremennoy klinicheskoy meditsiny, 6(3), 72-78.
Abaturov, A.Ye. (2008) Mikroelementnyy balans i protivoinfektsionnaya zashchita u detey. Zdorov'ye rebenka, 1 (10), 47-50.
Bulatov, V.P., Rylova, N.V. (2010) Mineral'nyy status u detey s zabolevaniyami organov pishchevareniya. Prakticheskaya meditsina, 42, 26-30.
Torshin, I.Yu., Gromova, O.A., Grishina, T.R., Rudakov, K.V. (2010) Iyerarkhiya vzaimodeystviy tsinka i zheleza: fiziologicheskiye, molekulyarnyye i klinichiskiye aspekty. Trudnyy patsiyent, 3, 100-101.
Marushko, Yu.V. (2013) Míkroelementy ta stan ímunítetu v dítey. Aktual'naya infektologiya, 1, 49-52.
Amare, B., Tafess, K., Moges, F. (2011). Levels of Serum Zinc, Copper and Copper/Zinc Ratio in Patients with Diarrhea and HIV Infection in Ethiopia. Journal of AIDS & Clinical Research, 2, 128-135.
Caulfield, Laura E. & Black, Robert E. Black (2004) Zinc deficiency, Comparative Quantification of Health Risks Global and Regional Burden of Disease Attributable to Selected Major Risk Factors. World Health Organization 2004. Retrieved from http://www.who.int/publications/cra/chapters/volume1/0257-0280.pdf?ua=1
Lahner, E., Persechino, S., Annibale, B. (2012) Micronutrients (Other than iron) and Helicobacter pylori Infection: A Systematic Review. Helicobacter, 17 (1), 1-15.
Yevseyeva, G.P., Suprun, S.V. (2006) Mikroelementnyy status u detey s ostroy pnevmoniyey v usloviyakh Priamur'ya. Vestnik OGU, 12-2, 93-96.
Janjetic, M.A., Goldman, C.G, Balcarce, N.E. (2010) Iron, zinc, and copper nutritional status in children infected with Helicobacter pylori. Journal of Pediatric Gastroenterology and Nutrition, 51 (1), 85-89.
Patel, A., Dibley, M.J., Mamtani, M., Badhoniya, N., Kulkarni, H. (2009) Zinc and copper supplementation in acute diarrhea in children: a double-blind randomized controlled trial. BMC Medicine, 7 (1), 22-34.
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