PSYCHOTIC AND MENTAL DISORDERS AND EFFECTIVENESS OF ART IN HIV-INFECTED INJECTION DRUG USERS
DOI:
https://doi.org/10.11603/1681-2727.2016.4.7210Keywords:
HIV infection, ART, CD4 cell, methadone, buprenorphine, injecting drug users.Abstract
In HIV-infected injecting drug users (IDUs) related mental disorders are often diagnosed (35-50 % of all patients). Methadone and buprenorphine substitution maintenance therapy (SMT) is a powerful element of HIV/AIDS prevention. Antiretroviral therapy (ART) is an integral part of medical care for HIV-positive patients.
The aim of our study was to evaluate the impact of psychotic and mental disorders on the effectiveness ART in HIV-infected IDUs with substitution therapy.
In the study we included 33 HIV-infected injection drug users, with evaluation degree of mental and psychotic disorders by BPRS and MADRS scales before SMT, ART and after 24 weeks of treatment.
Against the background of SMT to initiation of ART in all patients was marked reduction in the intensity of psychotic and depressive disorders, and after 24 weeks of ART reduction rate reached 12 points for the BPRS, and 6 points on the MADRS, respectively.
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