DOES CLINICAL REMISSION OF RECURRENT OBSTRUCTIVE BRONCHITIS ABSENCE OF IMMUNOLOGICAL CHANGES IN THE RESPIRATORY TRACT IN CHILDREN?

Abstract

SUMMARY. It was performed research of interleukin
4, 6, 8, 10 in the saliva of patients with recurrent
obstructive bronchitis (Rob) during the remission and
healthy children. Established that in the absence
of clinical manifestations in children continues Rob
immunopathological processes. It is shown that with a
history, clinical symptoms and results of determination
of interleukins 4, 6, 8, 10 in saliva within the group
of children with Rob can distinguish two subgroups:
patients with infection-associated infectious and allergic
genesis Rob disease. Children with allergic genesis of
the disease characteristic is burdened allergological
history in the family, atopic dermatitis during the first year
of life, development of exacerbation after contact with
animals or preferably during the flowering plants, the
absence of severe temperature reaction during bronchial
obstruction syndrome in combination with a significantly
increased content of interleukin 4 in saliva. Patients
infectious infection-associated Rob typical absence of
allergic disease in parents and other family members,
seasonality of exacerbations from November to April, the
development of exacerbations of bronchial obstruction
syndrome in combination with febrile fever and catarrhal
symptoms and increased contents in saliva levels of
interleukin 6, 8 and decrease contents of interleukin 10.
These features can be taken into account in assessing
the prognosis of the disease and identifying approaches
to differentiated treatment.
Key words: children, respiratory infections, obstructive
bronchitis.
Отримано 3.02.2016