ANALYSIS OF THE EPIDEMIOLOGICAL SITUATION OF TUBERCULOSIS IN TERNOPIL REGION FOR 2018-2024
DOI:
https://doi.org/10.11603/1681-2727.2025.3.15595Keywords:
epidemiology of tuberculosis, morbidity, bacterial isolates, destructive changes in the lungs, mortalityAbstract
SUMMARY. The aim of the work is to analyze the epidemic situation of tuberculosis in the Ternopil region and in Ukraine and compare the data obtained in the period before the COVID-19 pandemic, during the lockdown, and during the period of full-scale hostilities on the territory of Ukraine.
Materials and methods. A retrospective analysis of tuberculosis incidence, analysis of bacterial isolates, detection of destructive forms of pulmonary tuberculosis and mortality of such patients was conducted. The analysis was conducted on the basis of accounting and reporting forms of statistical reporting for 2018-2024 for the Ternopil region.
Results. The analysis of the epidemic situation of tuberculosis in Ternopil region and Ukraine for 2018-2024, in particular during the COVID-19 epidemic and under martial law, found that in 2020-2021 (COVID-19 pandemic) the number of detected tuberculosis patients significantly decreased compared to 2018-1019 (from 42.3 per 100 thousand population to 21.6 per 100 thousand population (-49 %). During the period of full-scale military operations, the incidence of tuberculosis in Ternopil region increased from 24.4 per 100 thousand population in 2021 to 32.9 per 100 thousand population in 2022 (+32.0 %). The highest proportion of bacterial isolates was recorded during the COVID-19 pandemic (75.2 %) and with the onset of martial law (76.3 %). A high level of destructive pulmonary tuberculosis was observed during the studied period, but the highest in 2020-2021 (57.0-63.2 %). In Ukraine, from 2018 to 2023, a gradual decrease in the mortality rate from tuberculosis was noted. Since 2022, the number of deaths within 1 year of observation has increased sharply.
Conclusions. The tuberculosis epidemic situation in the Ternopil region of Ukraine during the war remains tense. The dynamics of indicators were significantly influenced by the COVID-19 pandemic and hostilities in Ukraine. A significant number of bacterial isolates and destructive forms indicates late detection of tuberculosis.
References
MacNeil, A., Glaziou, P., Sismanidis, C., Date, A., Maloney, S., & Floyd, K. (2020). Global epidemiology of tuberculosis and progress toward meeting global targets – Worldwide, 2018. MMWR Morbidity and Mortality Weekly Report, 69(11), 281–285. https://doi.org/10.15585/mmwr.mm6911a2 DOI: https://doi.org/10.15585/mmwr.mm6911a2
O’Connell, J., McNally, C., Stanistreet, D., de Barra, E., & McConkey, S. J. (2023). Ending tuberculosis: The cost of missing the World Health Organization target in a low-incidence country. Irish Journal of Medical Science, 192(4), 1547–1553. https://doi.org/10.1007/s11845-022-03150-3 DOI: https://doi.org/10.1007/s11845-022-03150-3
GBD 2021 Tuberculosis Collaborators. (2024). Global, regional, and national age-specific progress towards the 2020 milestones of the WHO End TB Strategy: A systematic analysis for the Global Burden of Disease Study 2021. The Lancet Infectious Diseases, 24(7), 698–725. https://doi.org/10.1016/S1473-3099(24)00007-0 DOI: https://doi.org/10.1016/S1473-3099(24)00007-0
Falzon, D., Zignol, M., Bastard, M., Floyd, K., & Kasaeva, T. (2023). The impact of the COVID-19 pandemic on the global tuberculosis epidemic. Frontiers in Immunology, 14, 1234785. https://doi.org/10.3389/fimmu.2023.1234785 DOI: https://doi.org/10.3389/fimmu.2023.1234785
Valetskyi, Y. M., Nychyporuk, V. O., & Valetska, R. O. (2024). Modern features of the epidemiological situation of tuberculosis in Ukraine (Review). Tuberculosis, Lung Diseases, HIV Infection, 1(56), 103–108. https://doi.org/10.30978/TB2024-1-103 DOI: https://doi.org/10.30978/TB2024-1-103
Hryshchuk, L. A., Gzhesik, K., Wolf, S. B., Alexo, O. M., & Sanukevych, T. H. (2021). Епідеміологія туберкульозу в період пандемії COVID-19. Інфекційні хвороби, 1, 4–12. https://doi.org/10.11603/1681-2727.2021.1.11946 DOI: https://doi.org/10.11603/1681-2727.2021.1.11946
Krokva, D., Mori, H., Valenti, S., Remez, D., Hadano, Y., & Naito, T. (2025). Analysis of the impact of crises tuberculosis incidence in Ukraine amid pandemics and war. Scientific Reports, 15(1), 17045. https://doi.org/10.1038/s41598-025-01723-7 DOI: https://doi.org/10.1038/s41598-025-01723-7
ДУ Центр громадського здоров’я МОЗ України. (2020). Туберкульоз в Україні. Аналітично-статистичний довідник за 2020 рік. https://phc.org.ua/sites/default/files/users/user90/TB_surveillance_statistical-information_2020_dovidnyk.pdf
ДУ Центр громадського здоров’я МОЗ України. (2023). Туберкульоз в Україні. Аналітично-статистичний довідник за 2023 рік. https://phc.org.ua/kontrol-zakhvoryuvan/tuberkuloz/statistika-z-tb/analitichno-statistichni-materiali-z-tb
Wilczek, N. A., Brzyska, A., Bogucka, J., Sielwanowska, W. E., Żybowska, M., Piecewicz-Szczęsna, H., & Smoleń, A. (2023). The impact of the war in Ukraine on the epidemiological situation of tuberculosis in Europe. Journal of Clinical Medicine, 12(20), 6554. https://doi.org/10.3390/jcm12206554 DOI: https://doi.org/10.3390/jcm12206554
Hauer, B., Kröger, S., Haas, W., & Brodhun, B. (2023). Tuberculosis in times of war and crisis: Epidemiological trends and characteristics of patients born in Ukraine, Germany, 2022. Eurosurveillance, 28(24), 2300284. https://doi.org/10.2807/1560-7917.ES.2023.28.24.2300284 DOI: https://doi.org/10.2807/1560-7917.ES.2023.28.24.2300284
Butov, D., Feshchenko, Y., Chesov, D., Myasoedov, V., Kuzhko, M., Dudnyk, A., Reimann, M., Hryshchuk, L., … & Lange, C. (2023). National survey on the impact of the war in Ukraine on TB diagnostics and treatment services in 2022. International Journal of Tuberculosis and Lung Disease, 27(1), 86–88. https://doi.org/10.5588/ijtld.22.0563 DOI: https://doi.org/10.5588/ijtld.22.0563
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Copyright (c) 2025 Л. А. Грищук, Н. С. Кравченко, С. І. Корнага, В. Д. Рудик, М. В. Панькевич
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