REITER’S DISEASE IN THE PRACTICE OF AN INFECTIOUS DISEASE DOCTOR
DOI:
https://doi.org/10.11603/1681-2727.2025.2.15304Keywords:
urogenital chlamydiosis, mycoplasmosis, HLA-B27 antigen, reactive arthritis, pathogenesis, diagnosis, treatmentAbstract
SUMMARY. Reiter’s disease (Reiter’s syndrome – RS) is an infectious-allergic reactive condition that occurs after acute urogenital (urethritis, cystitis, cervicitis) or intestinal infections and is accompanied by chronologically related mainly asymmetric oligoarthritis of the lower extremities, concomitant ophthalmic (conjunctivitis, uveitis) and/or skin-mucosal changes (hyperkeratosis, dactylitis, urethritis, circinary balanitis and stomatitis).
Urogenital and enterocolitis forms of the disease are distinguished, and according to the features of the course can be acute, subacute and chronic forms. According to modern views, RS is a multisystemic disease, which is mainly registered in young men, positive for human leukocyte antigen B27, and is accompanied not only by reactive changes, but also by specific infectious arthritis.
A description of the clinical case of this disease is given.
References
Wallace, D. J., & Weisman, M. H. (2003, February). The physician Hans Reiter as prisoner of war in Nuremberg: a contextual review of his interrogations (1945–1947). In Seminars in arthritis and rheumatism (Vol. 32, No. 4, pp. 208–230). WB Saunders. DOI: https://doi.org/10.1053/sarh.2003.49995
Wikipedia. (2019). Reiter’s syndrome. Retrieved from: https://en.wikipedia.org/wiki/Reactive_arthritis.
Alebiosu, C. O., Raimi, T. H., Badru, A. I., Amore, O. O., Ogunkoya, J. O., & Odusan, O. (2004). Reiters syndrome – A case report and review of literature. African Health Sciences, 4(2), 136–138.
Bentaleb, I., Abdelghani, K. B., Rostom, S., Amine, B., Laatar, A., & Bahiri, R. (2020). Reactive arthritis: update. Current clinical microbiology reports, 7, 124–132. DOI: https://doi.org/10.1007/s40588-020-00152-6
Cheok, Y. Y., Lee, C. Y. Q., Cheong, H. C., Looi, C. Y., & Wong, W. F. (2020). Chronic inflammatory diseases at secondary sites ensuing urogenital or pulmonary Chlamydia infections. Microorganisms, 8(1), 127. DOI: https://doi.org/10.3390/microorganisms8010127
Can, Ö. Z. L. Ü. (Ed.). (2020). Lenfadenopatiye Multidisipliner Yaklaşım. Akademisyen Kitabevi.
Kasap, E. (2023). Chlamydia trachomatis: A Tiny Being beyond the Nature. IntechOpen. doi: 10.5772/intechopen.111425. DOI: https://doi.org/10.5772/intechopen.111425
Auñón, Á., Coifman, I., Blanco, A., García Cañete, J., Parrón-Cambero, R., & Esteban, J. (2022). Usefulness of a multiplex PCR assay for the diagnosis of prosthetic joint infections in the routine setting. Orthopaedic Surgery, 14(2), 383–388. DOI: https://doi.org/10.1111/os.13187
Bojović, J., Strelić, N., & Pavlica, L. (2014). Reiter’s syndrome: Disease of young men: Analysis of 312 patients. Medicinski pregled, 67(7-8), 222–230. DOI: https://doi.org/10.2298/MPNS1408222B
Khalmetova, F. I., Akhmedov, X. S., & Alibekova, G. A. (2023). Features of the course of the joint syndrome in various forms of reactive arthritis. Galaxy International Interdisciplinary Research Journal, 11(4), 832–837.
Jubber, A., & Moorthy, A. (2021). Reactive arthritis: a clinical review. Journal of the Royal College of Physicians of Edinburgh, 51(3), 288–297. DOI: https://doi.org/10.4997/jrcpe.2021.319
Filardo, S., Di Pietro, M., Frasca, F., Diaco, F., Scordio, M., Antonelli, G., ... & Sessa, R. (2021). Potential IFNγ modulation of inflammasome pathway in Chlamydia trachomatis infected synovial cells. Life, 11(12), 1359. DOI: https://doi.org/10.3390/life11121359
Turayev, K. F. I. S. M. (2022). Modern diagnostics of joint damage in patients with reactive arthritis.
Gupta, L., Naveen, R., Ahmed, S., Zanwar, A., Misra, D. P., Lawrence, A., ... & Aggarwal, A. (2021). Juvenile Reactive Arthritis and other Spondyloarthritides of Childhood: A 28-year Experience from India. Mediterranean journal of rheumatology, 32(4), 338. DOI: https://doi.org/10.31138/mjr.32.4.338
Pintea-Trifu, M. L., Bâlici, Ş., Siserman, C. V., Vică, M. L., & Matei, H. V. (2023). Chlamydia trachomatis and the HLA involvement in the development of infection and disease: a narrative review. Medicine and Pharmacy Reports, 96(4), 335. DOI: https://doi.org/10.15386/mpr-2593
Roodenrijs, N. M., Kedves, M., Hamar, A., Nagy, G., van Laar, J. M., van der Heijde, D., & Welsing, P. M. (2021). Diagnostic issues in difficult-to-treat rheumatoid arthritis: a systematic literature review informing the EULAR recommendations for the management of difficult-to-treat rheumatoid arthritis. RMD open, 7(1), e001511. DOI: https://doi.org/10.1136/rmdopen-2020-001511
Yang, P., Zhong, Z., Du, L., Li, F., Chen, Z., Zhu, Y., ... & Kijlstra, A. (2021). Prevalence and clinical features of systemic diseases in Chinese patients with uveitis. British Journal of Ophthalmology, 105(1), 75–82. DOI: https://doi.org/10.1136/bjophthalmol-2020-315960
Wendling, D., Prati, C., Chouk, M., & Verhoeven, F. (2020). Reactive arthritis: treatment challenges and future perspectives. Current rheumatology reports, 22, 1–7. DOI: https://doi.org/10.1007/s11926-020-00904-9
Liang, T. H., Lee, C. S., Lee, S. S., Wu, C. S., Chen, K. H., & Hsu, P. N. (2020). Efficacy and Safety of Opinercept Tumor Necrosis Factor Inhibitor Therapy for Drug-Refractory Rheumatoid Arthritis: A Randomized Clinical Trial. Arch Rheumatol 2020; 35 (x): ix. Arch Rheumatol ii (0.16% vs. 0.45%), 2, 2. DOI: https://doi.org/10.46497/ArchRheumatol.2020.7464
Zeng, H., Luo, B., Zhang, Y., Xie, Z., & Ye, Z. (2020). Treatment of reactive arthritis with biological agents: a review. Bioscience reports, 40(2), BSR20191927. DOI: https://doi.org/10.1042/BSR20191927
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