DAMAGE TO THE VOCAL CORDS IN CORONAVIRUS INFECTION
DOI:
https://doi.org/10.11603/1681-2727.2025.2.15297Keywords:
Coronavirus infection, vocal cord paresis/paralysis, complicationsAbstract
SUMMARY. Coronavirus infection causes a large number of complications in various organs and systems, given the tropism of the pathogenic virus to epithelial and nervous tissues. The SARS-CoV-2 is able to penetrate ganglia and nerves, causing functional and organic damage.
Vagus nerve damage leads to paresis or even paralysis of the vocal muscles with a high probability of aspiration.
Objective. To study the peculiarities of the development of vocal cord lesions in the context of coronavirus disease and identify possible ways to prevent complications.
Materials and Methods. We observed (consulted) a group of patients aged 30 to 80 years. All were hospitalised with coronavirus disease of varying severity and in the period of convalescence. Red blood cell saturation was in the range of 72–80 %. In addition to general research methods, laryngoscopy was used.
Results and Discussion. The 6 patients we observed had a common complaint of a dry, imperative cough, against which episodes of choking developed. Laryngoscopy revealed that 2 patients had mild right-sided paresis (inpatients) and 4 patients had left-sided paresis during the period of convalescence. Vitamins of group B, C and E were used in the course of treatment.
Conclusions. Coronavirus infection can lead to vagus nerve damage and vocal cord injury. In order to diagnose the complication in a timely manner, daily laryngoscopy with consultation of an ENT specialist and a neurologist is required.
References
Миколенко, А. З., Шандра, Ю. М. В., Федорович, М. Р., Трач Росоловська, С. В., & Орел, Ю. М. (2024). Вплив коронавірусної інфекції на стан різних систем організму людини. Вісник соціальної гігієни та організації охорони здоров’я України, 3, 41–45. doi: https://doi.org/10.11603/1681-2786.2024.3.14946 DOI: https://doi.org/10.11603/1681-2786.2024.3.14946
Міщенко, Т. С., Міщенко, В. М., Соколік, В. В., Фисенко, А. В., & Здесенко, І. В. (2022). Неврологічні порушення в пацієнтів, які перенесли COVID-19: як лікувати в умовах пандемії. Міжнародний неврологічний журнал, 17(6), 10–22. doi: https://doi.org/10.22141/2224-0713.17.6.2021.242231 DOI: https://doi.org/10.22141/2224-0713.17.6.2021.242231
Shehata, G. A., Lord, K. C., Grudzinski, M. C., Elsayed, M., Abdelnaby, R., & Elshabrawy, H. A. (2021). Neurological Complications of COVID-19: Underlying Mechanisms and Management. International journal of molecular sciences, 22(8), 4081. doi: https://doi.org/10.3390/ijms22084081 DOI: https://doi.org/10.3390/ijms22084081
Wan, D., Du, T., Hong, W., Chen, L., Que, H., Lu, Sh., & Peng, X. (2021). Neurological complications and infection mechanism of SARS-CoV-2. Sig Transduct Target Therapy, 6, 406. doi: https://doi.org/10.1038/s41392-021-00818-7 DOI: https://doi.org/10.1038/s41392-021-00818-7
Ткаченко, О. В. (2020). Ураження нервової системи при коронавірусній інфекції СOVID-19. Український неврологічний журнал, (1–2), 5–12. doi: https://doi.org/10.30978/UNJ2020-1-5 DOI: https://doi.org/10.30978/UNJ2020-1-5
Sharifian-Dorche, M., Huot, P., Osherov, M., Wen, D., Saveriano, A., Giacomini, P. S., Antel, J. P., & Mowla, A. (2020). Neurological complications of coronavirus infection; a comparative review and lessons learned during the COVID-19 pandemic. Journal of the neurological sciences, 417, 117085. doi: https://doi.org/10.1016/j.jns.2020.117085 DOI: https://doi.org/10.1016/j.jns.2020.117085
Бондар, М. В., Пилипенко, М. М., & Лоскутов, О. А. (2022). Ендотелій – головна мішень коронавірусної інфекції. Медицина невідкладних станів, 18(2), 13–19. doi: https://doi.org/10.22141/2224-0586.18.2.2022.1467 DOI: https://doi.org/10.22141/2224-0586.18.2.2022.1467
Малий, В. П., Асоян, І. М., Сай, І. В., & Андрусович, І. В. (2020). Патогенез коронавірусної інфекції COVID-19. Інфекційні хвороби, (3), 73–83. doi: https://doi.org/10.11603/1681-2727.2020.3.11555 DOI: https://doi.org/10.11603/1681-2727.2020.3.11555
Duzhyi, I., Yurchenko, A., Khyzhnia, Y., Klochko, A., Koshil, M., & Yurchenko, O. (2024). Features of the course of rare COVID-19 complications. Eastern Ukrainian Medical Journal, 12(3), 736–741. doi: https://doi.org/10.21272/eumj.2024;12(3):736-741 DOI: https://doi.org/10.21272/eumj.2024;12(3):736-741
Lisianiy, M. I., & Pedachenko, E. G. (2022). COVID-19: infection and neurological complications. Ukrainian Neurosurgical Journal, 28(1), 3–9. doi: https://doi.org/10.25305/unj.243599 DOI: https://doi.org/10.25305/unj.243599
Rapoport, S. K., Alnouri, G., Sataloff, R. T., & Woo, P. (2022). Acute Vocal Fold Paresis and Paralysis After COVID-19 Infection: A Case Series. The Annals of otology, rhinology, and laryngology, 131(9), 1032–1035. doi: https://doi.org/10.1177/00034894211047829 DOI: https://doi.org/10.1177/00034894211047829
Patel, S., & Vahabzadeh-Hagh, A. M. (2024). Breathy Dysphonia, Not Just a Pain in the Neck. Ear, Nose & Throat Journal, 103(8), 481–483. doi: https://doi.org/10.1177/01455613211069919 DOI: https://doi.org/10.1177/01455613211069919
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Copyright (c) 2025 І. Д. Дужий, А. Д. Клочко, В. І. Дужий, Є. В. Сміянов, І. А. Даниленко, А. В. Юрченко

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