THE ROLE OF PROBIOTIC CULTURES IN THE FORMATION OF THE GUT MICROBIOTA. THE GUT-BRAIN MICROBIOTA AXIS
DOI:
https://doi.org/10.11603/1681-2727.2024.4.15006Keywords:
probiotic, intestinal microbiota, enteric nervous system, gut-brain axis, stressAbstract
Probiotics and prebiotics modulate the gut-brain axis, which has a supportive effect on the central nervous system, and also reduces or controls the incidence of some mental disorders (depression, anxiety, autism, schizophrenia, and Alzheimer’s disease). The commensal microbiota plays a central role in the relationship between the gut microbiota and the central nervous system (the microbiota-gut-brain axis).
The gut-brain axis (GBA) consists of bidirectional communication between the central and enteric nervous systems, linking the emotional and cognitive centers of the brain with peripheral gut functions. As a result, modulation of the gut microbiota is considered a key aspect in the treatment of neurological disorders.
Research shows that the gut microbiome can influence the gut-brain axis and play an important role in the prevention and control of certain brain diseases, such as stress, Alzheimer’s disease, depression and insomnia.
Conclusions: The presented literature data can provide a motivational basis for conducting additional and in-depth research in the study of pathogenetic aspects of anxiety syndromes and stress.
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