PSEUDOMEMBRANEOUS COLITIS. IS THERE A DANGER FOR PREGNANTS?
DOI:
https://doi.org/10.11603/1681-2727.2024.2.14615Keywords:
pseudomembranous colitis, Clostridium difficile, antibiotics, pseudomembranes, pregnancyAbstract
SUMMARY. Pseudomembranous colitis (PMC) is a disease caused by Clostridium difficile, which mainly affects the lower parts of the digestive tract. The main risk factors are taking antibiotics, advanced age and long hospitalization.
The pathogenesis of the disease is not fully understood. Most often, the clinical picture is manifested by typical symptoms – diarrhea, pain in the lower quadrants of the abdomen, fever. Laboratory identification of C. difficile toxin in a stool sample and/or detection of pseudomembranes during endoscopy are required to confirm the diagnosis.
Today, conservative treatment is available, but many complications can occur, and in the most severe cases, surgical intervention may be necessary. Modern technologies are not yet able to help all patients, as refractory and recurrent forms of the disease are not rare.
C. difficile infection (CDI) can be particularly challenging in pregnant women, as it poses a serious health risk to both mother and child.
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