SCREENING PREDICTION OF ASCARIASIS AT CHRONIC PANCREATITIS
DOI:
https://doi.org/10.11603/1681-2727.2023.4.14249Keywords:
chronic pancreatitis, ascariasis, screening predictionAbstract
SUMMARY. The purpose of the research is to develop an algorithm for differential diagnosis and prediction of concomitant ascariasis in patients with chronic pancreatitis (CP) with visualization in the form of a decision tree.
Materials and methods. The research group consisted of 125 patients with CP combined with and without ascariasis. The diagnosis of CP was verified according to the clinical and statistical classification of diseases of the digestive organs. As a result of statistical processing, many rules are obtained that go from the root to each terminal node, contain inequalities for numerous attributes and inclusion conditions for categorical attributes.
Results. It was established that the use of the computerized decision tree method (data mining) is an effective means of building an optimal algorithm for predicting the comorbid course of CP and ascariasis (the error was 2.9 %). Clinical and instrumental (ultrasound) features of patients with CP are informative parameters for screening for the presence of ascariasis, which are presented as follows in order of decreasing significance: enlargement of the head of the pancreas, general weakness, hydrophilic structure of the pancreas, abdominal pain, nausea, unclear blurred contours of the pancreas, diarrhea, heaviness in the right or left hypochondrium, alternating constipation and diarrhea, bitterness in the mouth, inhomogeneous fine-grained echostructure of the pancreas, a feeling of fullness in the abdomen, duration of CP. This is important for determining the correct tactics of further diagnosis, treatment, and rehabilitation of patients with a combined course of CP and ascariasis.
Conclusion. For screening prediction of the presence of comorbid ascariasis in CP and determination of rational tactics for further diagnosis, treatment, and rehabilitation of patients with a combined course of CP and ascariasis at the primary level of medical care, it was recommended to use the computerized decision tree method (data mining).
References
Leung, A. K. C., Leung, A. A. M., Wong, A. H. C., & Hon, K. L. (2020). Human Ascariasis: An Updated Review. Recent Patents on Inflammation & Allergy Drug Discovery, 14(2), 133–145. https://doi.org/10.2174/1872213X14666200705235757 DOI: https://doi.org/10.2174/22122710MTA3eOTIl5
Babinets, L. S., Droniak, Iu. V., Pliashko, K. O., & Babinets, A. I. (2014). Efficiency of etiologic correction of concomitant ascaridosis in the complex treatment of chronic pancreatitis, Likarska sprava – Medical Case, 11, 116–118. DOI: https://doi.org/10.31640/LS-2014-11-22
Yamawaki, H., Futagami, S., Kaneko, K., Agawa, S., Higuchi, K., Murakami, M., Wakabayashi, M., Sakasegawa, N., Kodaka, Y., Ueki, N., Gudis, K., Kawamoto, C., & Iwakiri, K. (2019). Camostat Mesilate, Pancrelipase, and Rabeprazole Combination Therapy Improves Epigastric Pain in Early Chronic Pancreatitis and Functional Dyspepsia with Pancreatic Enzyme Abnormalities. Digestion, 99 (4), 283–292. https://doi.org/10.1159/000492813 DOI: https://doi.org/10.1159/000492813
Babynets, L., & Halabitska, I. (2021). Evaluation of Pancreatotropic and Joint Efficiency of Intracellular Systemic Enzyme in Osteoarthritis. Family Medicine, (5-6), 66–69. https://doi.org/10.30841/2307-5112.5-6.2020.225452 DOI: https://doi.org/10.30841/2307-5112.5-6.2020.225452
Halabitska, I. M., & Babinets, L. S. (2021). Different consequences of the treatment of osteoarthritis in gastrointestinal comorbidity with exocrine pancreatic insufficiency. Family Medicine & Primary Care Review, 23(4), 422-428. https://doi.org/10.5114/fmpcr.2021.108207 DOI: https://doi.org/10.5114/fmpcr.2021.108207
Wakabayashi, M., Futagami, S., Yamawaki, H., Tatsuguchi, A., Kaneko, K., Agawa, S., Higuchi, K., Sakasegawa, N., Murakami, M., Akimoto, T., Kodaka, Y., Ueki, N., Gudis, K., Kawamoto, C., Akamizu, T., Sakamoto, C., & Iwakiri, K. (2018). Comparison of clinical symptoms, gastric motility and fat intake in the early chronic pancreatitis patients with anti-acid therapy-resistant functional dyspepsia patients. PloS One, 13(11), e0205165. https://doi.org/10.1371/journal.pone.0205165 DOI: https://doi.org/10.1371/journal.pone.0205165
Bouree, P., Barthod, F., & Chagnon, S. (2005). Ascaris in gallbladder: report of a case and review. Journal of the Egyptian Society of Parasitology, 35(2), 491–496.
Babinets, L. S., Halabitska, I. M., Borovyk, I. O., Redkva, O. V., & Sasyk, H. M. (2020). The influence of exocrine pancreatic insufficiency in the formation of osteopenia in patients with primary osteoarthritis. Wiadomosci lekarskie (Warsaw, Poland: 1960), 73(10), 2238–2240. DOI: https://doi.org/10.36740/WLek202010125
Kolleri, J. J., Thabet, A. M. J., Mohammedain, S., Sajid, S., Ahmed, Z., & Momin, U. (2023). A Case Report on Biliary Ascariasis. Cureus, 15(1), e33323. https://doi.org/10.7759/cureus.33323 DOI: https://doi.org/10.7759/cureus.33323
Babinets, L. S., Dronyak, Y. V., & Меlnyk, N. A. (2018). Concomitant ascariasis as a factor in reducing the quality of life of patients with chronic pancreatitis. Wiadomosci lekarskie (Warsaw, Poland: 1960), 71(7), 1250–1253.
Racioppi, F.A., Cestari, M., Puccar, P. (2020) Ascaridiosis en la vía biliar intrahepática: a propósito de un caso pediátrico [Ascariasis in the intrahepatic biliary duct: about a case in pediatrics]. Arch Argent Pediatr., 118(5), e476-e479. https://doi.org/10.5546/aap.2020.e476
Racioppi, F. A., Cestari, M., Puccar, P., El Kik, S., Ferrari, M., Lipsich, J., Garriga, M., Sarkis, C., & Paulin, P. (2020). Ascaridiosis en la vía biliar intrahepática: a propósito de un caso pediátrico [Ascariasis in the intrahepatic biliary duct: about a case in pediatrics]. Archivos Argentinos de Pediatria, 118(5), e476–e479. https://doi.org/10.5546/aap.2020.e476 DOI: https://doi.org/10.5546/aap.2020.e476
Evangelista, F. M. D., van Vliet, A. H. M., Lawton, S. P., & Betson, M. (2023). In silico design of a polypeptide as a vaccine candidate against ascariasis. Scientific reports, 13(1), 3504. https://doi.org/10.1038/s41598-023-30445-x DOI: https://doi.org/10.1038/s41598-023-30445-x
Djune-Yemeli, L., Nana-Djeunga, H. C., Lenou-Nanga, C. G., Donfo-Azafack, C., Domche, A., Fossuo-Thotchum, F., Niamsi-Emalio, Y., Ntoumi, F., & Kamgno, J. (2020). Serious limitations of the current strategy to control Soil-Transmitted Helminths and added value of Ivermectin/Albendazole mass administration: A population-based observational study in Cameroon. PLoS Neglected Tropical Diseases, 14 (11), e0008794. https://doi.org/10.1371/journal.pntd.0008794 DOI: https://doi.org/10.1371/journal.pntd.0008794
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2023 Л. С. Бабінець, І. М. Галабіцька
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Journal Infectious Disease (Infektsiini Khvoroby) allows the author(s) to hold the copyright without registration
Users can use, reuse and build upon the material published in the journal but only for non-commercial purposes
This journal is available through Creative Commons (CC) License BY-NC "Attribution-NonCommercial" 4.0
