MIXED INFECTION OF COVID-19 AND INFLUENZA: CURRENT STATE OF THE ISSUE
DOI:
https://doi.org/10.11603/1681-2727.2023.1.13919Keywords:
coronavirus disease COVID-19, influenza, viral infection, clinic, diagnosis, treatmentAbstract
SUMMARY. The paper presents current data on mixed infection caused by SARS-CoV-2 and the influenza virus at various stages of the COVID-19 pandemic. It is noted that the onset of the COVID-19 pandemic coincided with a seasonal increase in the incidence of influenza, which led to mixed infection and increased the risk of a fatal outcome. Despite the limited resources for testing for other respiratory infections during the COVID-19 pandemic, the data presented in the literature indicate significant changes in the course of mixed infection depending on the circulation of the dominant strain of SARS-CoV-2. During the circulation of the Omicron SARS-CoV-2 strain, there is an increase in the number of influenza cases and, accordingly, mixed infection. The frequency of mixed infection of COVID-19 and influenza is not high. However, in these cases, a greater severity of clinical symptoms and the risk of a more severe course of the disease are characteristic. This requires timely testing for both of these infections to decide the choice of antiviral treatment. The study of the peculiarities of “cytokine storm” formation is a promising direction of research for the further development of immunotropic treatment differential means. Preventive measures should include vaccination against both COVID-19 and influenza in the context of the COVID-19 pandemic and seasonal influenza.
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