LONG-COVID AND ASSOCIATED INJURIES OF THE CARDIOVASCULAR AND NERVOUS SYSTEMS
DOI:
https://doi.org/10.11603/1681-2727.2022.4.13701Keywords:
coronavirus infection, Long-COVID, clinical signs, cardiovascular system, nervous system, blood coagulation system, myocarditis, pericarditis, endothelium, brain-heart axis, stroke, good health and well-beingAbstract
In order to study the peculiarities of the clinical course of Long-COVID, a review of scientific publications containing data on Long-COVID as a separate pathological condition, relevant information on its manifestations, and some pathophysiological mechanisms leading to the development of lesions of the cardiovascular and nervous systems was conducted.
Conclusions. The definition of the term Long-COVID as a separate condition in the course of coronavirus disease took place in several stages. Symptoms of Long-COVID are associated with damage to almost all organ systems. Cardiovascular lesions are among the most common, and there is evidence that the mechanism of such lesions is associated with disorders in the blood clotting system with the formation of microthrombi. In addition, cardiovascular damage is the main cause of death in patients with Long-COVID. The gender ratio in the case of cardiovascular damage is the same, while damage to the nervous system and other organs and systems occurs mainly in women. Some of the existing data have already found additional confirmation in the results of recent studies, while others need to be confirmed.
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