KAWASAKI-LIKE MULTISYSTEM INFLAMMATORY SYNDROME ASSOCIATED WITH COVID-19 IN CHILDREN AND ADULTS
DOI:
https://doi.org/10.11603/1681-2727.2022.2.13189Keywords:
coronavirus disease, COVID-19, Kawasaki syndrome, multisystem inflammatory syndromeAbstract
SUMMARY. Fighting the consequences of COVID-19 is a serious and very urgent task facing modern medicine. COVID-19 often has a severe course and is accompanied by multiorgan damage, systemic immune inflammation, coagulopathy, neuroendocrine and metabolic disorders, functional and psychoemotional disorders.
There are more reports of an increase in cases of hyperinflammatory Kawasaki-like syndrome in children and adults with COVID-19. The pathogenesis of this post-Covid syndrome has not yet been fully understood, although it has been established that it is a post-viral and immune response to SARS-CoV-2.
The symptoms of hyperinflammatory Kawasaki-like syndrome resemble Kawasaki syndrome, but there are significant differences: patients are older, more often there are signs of damage to the gastrointestinal tract, respiratory tract, heart, that is, it has systemic features and is sometimes considered a «constellation» of Kawasaki disease.
The purpose of the study was to analyze literature data and familiarize doctors with the pathogenesis, clinical picture, diagnosis of post-Covid hyperinflammatory syndrome, which mimics Kawasaki disease in patients with COVID-19, which often requires immunomodulating and other therapy options..
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