LISTERIOUS MENINGITIS IN CHILDREN – THE STATUS OF THE PROBLEM

Authors

DOI:

https://doi.org/10.11603/1681-2727.2021.4.12841

Keywords:

listeriosis, meningitis, children, clinic, treatment

Abstract

The article highlights and summarizes the literature data on the incidence, features of the listeriosis clinical course and its treatment in children, modern views on the problem. The most common clinical form is listeriosis meningitis. It is registered in Ukraine in the form of sporadic cases. A rare case of listeriosis with the development of meningitis was described in a 4-year-old girl with a prolonged course of the disease and the lack of a clear parallel between the general condition and the dynamics of changes in the cerebrospinal fluid. The applied set of treatment measures, which included powerful antibacterial therapy, helped to achieve complete clinical recovery of the sick child on the 28th day of inpatient treatment. This case argues the feasibility of taking into account the results of cerebrospinal fluid bacterioscopic examination, namely – the presence of gram-positive rods, and the release of L.monocytogenes in bacteriological examinations.

Author Biographies

O. V. Prokopiv, Danylo Halytsky Lviv National Medical University

MD, Professor at the Pediatric Infectious Diseases Department, Danylo Halytskyi Lviv National Medical University

S. A. Lysheniuk, Danylo Halytsky Lviv National Medical University

PhD, Associate Professor at the Pediatric Infectious Diseases Department, Danylo Halytskyi Lviv National Medical University

N. M. Prykuda, Danylo Halytsky Lviv National Medical University

PhD, assistant at the Infectious Diseases Department, Danylo Halytskyi Lviv National Medical University

References

Halbedel, S., Wilking, H., Holzer, A., Kleta, S., Fischer, M. A., Lüth, S., ... & Flieger, A. (2020). Large nationwide outbreak of invasive listeriosis associated with blood sausage, Germany, 2018–2019. Emerging Infectious Diseases, 26 (7), 1456.

Smith, A.M., Tau, N.P., Smouse, S.L., Allam, M., Ismail, A., Ramalwa, N.R., ... & Thomas, J. (2019). Outbreak of Listeria monocytogenes in South Africa, 2017–2018: Laboratory activities and experiences associated with whole-genome sequencing analysis of isolates. Foodborne Pathogens and Disease, 16 (7), 524-530. Retrieved from: https://doi.org/10.1089/fpd.2018.2586

Lee, J.E., Cho, W.K., Nam, C.H., Jung, M.H., Kang, J.H., & Suh, B.K. (2010). A case of meningoencephalitis caused by Listeria monocytogenes in a healthy child. Korean Journal of Pediatrics, 53 (5), 653. doi.org/10.3345/kjp.2010.53.5.653

Villa, G., Diana, M.C., Solari, N., Bandettini, R., Sorrentino, S., Loy, A., ... & Renna, S. (2017). Listeria meningitis in an immunocompetent child. Pediatric Emergency Care, 33 (8), 579-581. doi.org/10.1097/PEC.0000000000000687.

Castellazzi, M.L., Marchisio, P., & Bosis, S. (2018). Listeria monocytogenes meningitis in immunocompetent and healthy children: a case report and a review of the literature. Italian Journal of Pediatrics, 44 (1), 1-5. doi.org/10.1186/s13052-018-0595-5

Ruppitsch, W., Prager, R., Halbedel, S., Hyden, P., Pietzka, A., Huhulescu, S., ... & Wilking, H. (2015). Ongoing outbreak of invasive listeriosis, Germany, 2012 to 2015. Eurosurveillance, 20 (50), 30094.

Koopmans, M.M., Bijlsma, M.W., Brouwer, M.C., van de Beek, D., & van der Ende, A. (2017). Listeria monocytogenes meningitis in the Netherlands, 1985–2014: a nationwide surveillance study. Journal of Infection, 75 (1), 12-19.

Filipello, V., Mughini-Gras, L., Gallina, S., Vitale, N., Mannelli, A., Pontello, M., ... & Lomonaco, S. (2020). Attribution of Listeria monocytogenes human infections to food and animal sources in Northern Italy. Food Microbiology, 89, 103433. DOI: 10.1016/j.fm.2020.103433.

Charlier, C., Perrodeau, É., Leclercq, A., Cazenave, B., Pilmis, B., Henry, B., ... & Beaune, B. (2017). Clinical features and prognostic factors of listeriosis: the MONALISA national prospective cohort study. The Lancet Infectious Diseases, 17 (5), 510-519. DOI: 10.1016/S1473-3099(16)30521-7.

State Institution «Public Health Center of the Ministry of Health of Ukraine». (2022). Listeriosis. https://phc.org.ua/kontrol-zakhvoryuvan/inshi-infekciyni-zakhvoryuvannya/listerioz

Madjunkov, M., Chaudhry, S., & Ito, S. (2017). Listeriosis during pregnancy. Archives of Gynecology and Obstetrics, 296 (2), 143-152. DOI: 10.1007/s00404-017-4401-1.

Charlier, C., Disson, O., & Lecuit, M. (2020). Maternal-neonatal listeriosis. Virulence, 11 (1), 391-397. DOI: 10.1080/21505594.2020.1759287.

Tai, Y.L., Chi, H., Chiu, N.C., Lin, C.Y., Cheng, J.L., Hsu, C.H., ... & Huang, F.Y. (2020). Clinical features of neonatal listeriosis in Taiwan: a hospital-based study. Journal of Microbiology, Immunology and Infection, 53 (6), 866-874. DOI: 10.1016/j.jmii.2019.08.001.

Zinchuk, O.M., Zadorozhny, A.M., Prykuda, N.M., & Sosna, G.P. (2018). Clinical and etiological characteristics of lethal cases of purulent meningitis in adults. Bukovynskyy medychnyy visnyk – Bukovynian Medical Bulletin, 22 (1), 36-45. doi.org/10.24061/2413-0737.XXII.1.85.2018.6

Ghosh, P., Zhou, Y., Richardson, Q., & Higgins, D.E. (2019). Characterization of the pathogenesis and immune response to Listeria monocytogenes strains isolated from a sustained national outbreak. Scientific Reports, 9 (1), 1-12. doi.org/10.1038/s41598-019-56028-3

Ulloa-Gutierrez, R., Avila-Agüero, M. L., & Huertas, E. (2004). Fulminant Listeria monocytogenes meningitis complicated with acute hydrocephalus in healthy children beyond the newborn period. Pediatric Emergency Care, 20 (4), 233-237. doi.org/10.1097/01.pec.0000121243.99242.a9.

Published

2022-04-11

How to Cite

Prokopiv, O. V., Lysheniuk, S. A., & Prykuda, N. M. (2022). LISTERIOUS MENINGITIS IN CHILDREN – THE STATUS OF THE PROBLEM. Infectious Diseases – Infektsiyni Khvoroby, (4), 64–67. https://doi.org/10.11603/1681-2727.2021.4.12841

Issue

Section

Brief reports