ADEQUATE IMMUNIZATION AND CREATION OF COLLECTIVE IMMUNITY FROM COVID-19 IN MODERN CONDITIONS

Authors

  • A. M. Bondarenko Kryvy Rih National University
  • L. A. Bondarenko Dnipro State Medical University

DOI:

https://doi.org/10.11603/1681-2727.2021.4.12839

Keywords:

COVID-19, vaccination, legal framework, safety profile

Abstract

The authors note the significant anti-epidemic failure of currently used coronavirus vaccines, despite the significant level of immunization of the population. Nevertheless, vaccination avoids severe or extremely severe COVID-19 and death from the disease.

The officially announced excess of tension and protective activity of post-vaccination anti-vaccine immunity compared to post-infection is discussed.

The problems of the legal basis of vaccination against COVID-19 in Ukraine are considered. It is proposed to include in this regulatory framework a new clinical standard (protocols, regulations, instructions), which oblige to determine before vaccination for each patient the feasibility of vaccination against COVID-19 and mandatory specificity of the safety profile of vaccination against COVID-19 and individual safety of the specific vaccine used.

The author’s algorithm for assessing the feasibility and safety of vaccination from COVID-19 is presented.

Author Biographies

A. M. Bondarenko, Kryvy Rih National University

MD, Head of the Department of Ecology, Kryvy Rih National University, Infectious Diseases Specialist, Kryvy Rih City Clinical Hospital № 2

L. A. Bondarenko, Dnipro State Medical University

intern obstetrician-gynecologist «Dnipropetrovsk Regional Perinatal Center», Dnipro State Medical University

References

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WHO Coronavirus (COVID-19) Global Ukraine. – https://covid19.who.int/region/euro/country/ua, 08/11/2021

WHO (08/11/21). Status of COVID-19. Vaccines within WHO EUL/PQ evaluation process. – https://extranet.who.int/pqweb/sites/default/files/documents/Status_COVID_VAX_20Oct2021.pdf

Bondarenko, A. M., Kopcha, V. S. (2021). Practical assessment of the effectiveness, feasibility and safety of vaccines from COVID 19. Health of Ukraine. Thematic issue “Pulmonology, Allergology, Rhinolaryngology”, 1(54), 3-6. – https://health-ua.com/article/65448-praktichna-otcnka-efektivnost--dotclnost-tabezpechnost-zastosuvannya--vaktc [in Ukrainian].

Bondarenko, A. M. (2019). Vaccination – assessment of feasibility and risks. Infectious diseases – Infektsiyni khvoroby, 2, 77-95 [in Ukrainian].

CDC (2021). Vaccination provides more reliable protection than COVID-19. – https://www.cdc.gov/media/releases/2021/s1029-Vaccination-Offers-

Ministry of Health of the Russian Federation, Federal Service for Surveillance in Healthcare (Roszdravnadzor). (2021). About the international format for assessing the level of immunoglobulins, including IgG to SARS-CoV-2, 02i-840/21, 3 р. [in Russian].

Pfizer antiviral slashes COVID-19 hospitalization. Given early infection experimental pill prevents severe diseases, trial suggest. Science, 05/11/2021. – https://www.science.org/content/article/pfizer-antiviral-slashes-covid-19-hospitalizations 08/11/2021

Pfizer’s Covid-19 Oral Antiviral Treatment Paxlovid Reduces Risk of Hospitalization and Death. Drugs.com, Clinical Trials. – https://www.drugs.com/clinical_trials/pfizer-s-covid-19-oral-antiviral-paxlovid-Reduces-risk-hospitalization-death-19762.html 08/11/2021

Merck and Ridgeback’s Investigational Oral Antiviral Molnupiravir Reduced Risk of Hospitalization or Death Approximately 50% Compared to Placebo for Patients with Mild Interim Analysis of Phase 3 Study. Drugs.com, Clinical Trials. – https://www.drugs.com/clinical_trials/merck-ridgeback-s-investigational-oral-antiviral-molnupiravir-reduced-risk-hospitalization-death-19657.html 08.11.2021

Published

2022-04-11

How to Cite

Bondarenko, A. M., & Bondarenko, L. A. (2022). ADEQUATE IMMUNIZATION AND CREATION OF COLLECTIVE IMMUNITY FROM COVID-19 IN MODERN CONDITIONS. Infectious Diseases – Infektsiyni Khvoroby, (4), 48–57. https://doi.org/10.11603/1681-2727.2021.4.12839

Issue

Section

Discussion and releable