DYNAMICS OF VITAMIN D IN BLOOD OF PATIENTS WITH CHRONIC VIRAL HEPATITIS WITH THE APPLICATION OF CHOLECALCIFEROL IN ANTI-VIRAL THERAPY

Authors

DOI:

https://doi.org/10.11603/1681-2727.2021.4.12837

Keywords:

chronic viral hepatitis C, vitamin D, vitamin D deficiency

Abstract

Viral hepatitis C (HCV) is the second most common cause of liver cirrhosis (LC) and hepatocellular carcinoma (HCC) in the world. In Ukraine, about 1 300 000 people are infected with hepatitis C virus, 25 % of whom, the disease progresses over time in the LC and HCC, which is precisely what makes HCV a serious problem for the domestic health care system. The work is based on the study of the dynamics of the vitamin D content in patients with chronic viral hepatitis C deficiency and vitamin D deficiency when using colecalciferol together with antiviral therapy.

Author Biographies

M. A. Nikolaychuk, Dnipro State Medical University

PhD, teaching Assistant at the Department of Infectious Diseases, Dnipro State Medical University

L. R. Shostakovych-Koretska, Dnipro State Medical University

MD, Professor at the Department of Infectious Diseases, Dnipro State Medical University

References

Holick, M.F., Binkley, N.C., Bischoff-Ferrari, H.A., Gordon, C.M., Hanley, D.A., Heaney, R.P., ... & Weaver, C.M. (2011). Evaluation, treatment, and prevention of vitamin D deficiency: an Endocrine Society clinical practice guideline. The Journal of Clinical Endocrinology & Metabolism, 96 (7), 1911-1930.

Nikolaychuk, M., Shostakovych-Koretska, L., & Sheveleva, E. (2018). Vitamin D level in patients with Chronic Viral Hepatitis C. 4th Central and Eastern European Meeting on Viral Hepatitis and HIV. Reviews in Antiviral Therapy & Infectious Diseases, 12, 46-48 [in Ukrainian].

Shostakovych-Koretska, L.R., Nikolaychuk, M.A., Budayeva, I.V., Shevchenko-Makarenko, O.P., Lytvyn, K.Yu., & Biletska, S.V. (2019). Comparative analysis with vitamin D in patients with chronic viral hepatitis C and healthy people. Medychni perspektyvy – Medical Perspectives, 24 (4), 94-101 [in Ukrainian].

Blaya, C. (2019). Cyberhate: A review and content analysis of intervention strategies. Aggression and Violent Behavior, 45, 163-172. URL: https://www.R-project.org/

Hahne, F., LeMeur, N., Brinkman, R. R., Ellis, B., Haaland, P., Sarkar, D., ... & Gentleman, R. (2009). flowCore: a Bioconductor package for high throughput flow cytometry. BMC Bioinformatics, 10 (1), 1-8. Retrieved from: http://lmdvr.r-forge.r-project.org

Firke, S., Haid, C., Knight, R., & Denney, B. (2018). Package janitor; Simple tools for examining and cleaning dirty data. R (>= 3.1. 2). Retrieved from: https://cran.r-project.org/package=janitor

Published

2022-04-11

How to Cite

Nikolaychuk, M. A., & Shostakovych-Koretska, L. R. (2022). DYNAMICS OF VITAMIN D IN BLOOD OF PATIENTS WITH CHRONIC VIRAL HEPATITIS WITH THE APPLICATION OF CHOLECALCIFEROL IN ANTI-VIRAL THERAPY. Infectious Diseases – Infektsiyni Khvoroby, (4), 32–35. https://doi.org/10.11603/1681-2727.2021.4.12837

Issue

Section

Original investigations