LEVEL OF NON-SPECIFIC REACTION OF GENERAL NATURE. REACTIVE RESPONSE OF NEUTROPHIL GRANULOCYTES AND NON-SPECIFIC IMMUNE ANTI-INFECTIOUS PROTECTION OF COVID-19 PATIENTS

Authors

DOI:

https://doi.org/10.11603/1681-2727.2021.4.12834

Keywords:

coronavirus disease, inflammatory reaction, factors of nonspecific anti-infective protection

Abstract

Coronavirus disease is an acute respiratory viral infection with airborne transmission caused by a new coronavirus (SARS-CoV-2) that affects people of all ages and occurs asymptomatically, mildly and severely with atypical pneumonia, respiratory syndrome, in which death is possible.

The aim of the study was to determine the level of nonspecific response of a general nature and the level of reactive response of neutrophilic granulocytes of peripheral blood, nonspecific immune anti-infective protection of patients with coronavirus disease when admitted to hospital.

Nonspecific factors and mechanisms of anti-infective protection are involved in the formation of adaptive immunity in the early stages and in the final states, which increases their role in anti-infective protection.

Therefore, establishing the level of nonspecific response of general non-specific anti-infective protection of patients with coronavirus disease and reactive response of neutrophilic granulocytes, which play a key role, given their largest population of immunocompetent blood cells, in non-specific anti-infective protection is necessary and relevant.

Author Biographies

V. D. Moskaliuk, Bukovynian State Medical University

MD, Professor, Head at the Department of Infectious Diseases and Epidemiology, Bukovynian State Medical University

S. S. Kryvetska, Bukovynian State Medical University

Assistant at the Department of Infectious Diseases and Epidemiology, Bukovynian State Medical University

I. V. Balaniuk, Bukovynian State Medical University

PhD, Associate Professor at the Department of Infectious Diseases and Epidemiology, Bukovynian State Medical University

I. V. Rudan, Bukovynian State Medical University

Assistant Professor at the Department of Infectious Diseases and Epidemiology, Bukovynian State Medical University

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Published

2022-04-11

How to Cite

Moskaliuk, V. D., Kryvetska, S. S., Balaniuk, I. V., & Rudan, I. V. (2022). LEVEL OF NON-SPECIFIC REACTION OF GENERAL NATURE. REACTIVE RESPONSE OF NEUTROPHIL GRANULOCYTES AND NON-SPECIFIC IMMUNE ANTI-INFECTIOUS PROTECTION OF COVID-19 PATIENTS. Infectious Diseases – Infektsiyni Khvoroby, (4), 14–20. https://doi.org/10.11603/1681-2727.2021.4.12834

Issue

Section

Original investigations