CLINICAL AND EPIDEMIOLOGICAL FEATURES OF PARASITIC INVASION OF BLASTOCYSTIS SPP.

Authors

  • V. R. Shahinian L. Hromashevskyi Institute of Epidemiology and Infectious Diseases, NAMS of Ukraine
  • I. V. Filchakov L. Hromashevskyi Institute of Epidemiology and Infectious Diseases, NAMS of Ukraine
  • O. P. Danko L. Hromashevskyi Institute of Epidemiology and Infectious Diseases, NAMS of Ukraine
  • H. V. Sopil L. Hromashevskyi Institute of Epidemiology and Infectious Diseases, NAMS of Ukraine
  • O. P. Diachenko L. Hromashevskyi Institute of Epidemiology and Infectious Diseases, NAMS of Ukraine

DOI:

https://doi.org/10.11603/1681-2727.2020.3.11556

Keywords:

epidemiology, clinical features, invasion of Blastocystis spp

Abstract

The aim of the work is to generalize modern views on epidemiological and clinical features of parasitic invasion of Blastocystis spp.

The analysis of modern ideas and data of own researches on prevalence and role of Blastocystis spp. in pathology of the gastrointestinal tract, in particular irritable bowel syndrome (IBS) was performed. The state of studying mechanisms of influence of intestinal microbiota on the pathogenesis of IBS and participation in this blastocyst invasion is covered. The issue of the prevalence of Blastocystis spp. in persons with immunodeficiency is reviewed. Based on literature data and own research, the low prevalence of Blastocystis spp. in HIV-positive patients is noted. Significant differences in the frequency of detection of different intestinal protozoa in HIV-positive patients may confirm the higher pathogenicity of Cryptosporidium spp in comparison with Blastocystis spp. Given the ambiguity of literary data on the pathogenic potential of the parasite blastocyst invasion was considered from the standpoint of the parasitic system as the biological basis of the epidemic process. The generalization of the existing of epidemiological and clinical data suggested that further evolutionary changes in biological properties of Blastocystis spp. will occur in the direction of reducing the virulence of the parasite, which will contribute to the long-term persistence of the pathogen in the host organism.

Conclusion. The data obtained to date may indicate insignificant epidemiological significance of blastocyst invasion against the background of a significant prevalence of the parasite in the human population. Lack of consensus on the clinical significance of Blastocystis spp. in the formation and development of chronic pathology of the gastrointestinal tract confirms the need for in-depth study of the subtle mechanisms of interaction between the parasite and the host, taking into account the intensity of invasion, intestinal microbiota and immunological resistance of the organism.

Author Biographies

V. R. Shahinian, L. Hromashevskyi Institute of Epidemiology and Infectious Diseases, NAMS of Ukraine

MD, Senior researcher, Head of the Department of Diagnostics of Infectious and Parasitic Diseases, L. V. Hromashevskyi Institute of Epidemiology and Infectious Diseases, NAMS of Ukraine

I. V. Filchakov, L. Hromashevskyi Institute of Epidemiology and Infectious Diseases, NAMS of Ukraine

PhD (Medicine), Senior researcher, Leading researcher of the Department of Diagnostics of Infectious and Parasitic Diseases, L. V. Hromashevskyi Institute of Epidemiology and Infectious Diseases, NAMS of Ukraine

O. P. Danko, L. Hromashevskyi Institute of Epidemiology and Infectious Diseases, NAMS of Ukraine

PhD (Medicine), Senior researcher of the Department of Diagnostics of Infectious and Parasitic Diseases, L.V. Hromashevskyi Institute of Epidemiology and Infectious Diseases, NAMS of Ukraine

H. V. Sopil, L. Hromashevskyi Institute of Epidemiology and Infectious Diseases, NAMS of Ukraine

Researcher of Department of Diagnostics of Infectious and Parasitic Diseases, L. V. Hromashevskyi Institute of Epidemiology and Infectious Diseases, NAMS of Ukraine

O. P. Diachenko, L. Hromashevskyi Institute of Epidemiology and Infectious Diseases, NAMS of Ukraine

Junior researcher of Department of Diagnostics of Infectious and Parasitic Diseases, L. V. Hromashevskyi Institute of Epidemiology and Infectious Diseases, NAMS of Ukraine

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Published

2020-12-04

How to Cite

Shahinian, V. R., Filchakov, I. V., Danko, O. P., Sopil, H. V., & Diachenko, O. P. (2020). CLINICAL AND EPIDEMIOLOGICAL FEATURES OF PARASITIC INVASION OF BLASTOCYSTIS SPP. Infectious Diseases – Infektsiyni Khvoroby, (3), 84–90. https://doi.org/10.11603/1681-2727.2020.3.11556

Issue

No. 3 (2020)

Section

Reviews and lectures

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