THE EFFECT OF ANTISEPTICS ON THE MICROFLORA OF PERIOPERATIVE INFECTIOUS COMPLICATIONS IN PATIENTS WITH BENIGN PROSTATIC HYPERPLASIA

Authors

DOI:

https://doi.org/10.11603/2414-4533.2025.2.15378

Keywords:

benign prostatic hyperplasia, postoperative infection, microorganisms, antiseptics

Abstract

The aim of the work: to study the effectiveness of antiseptic agents in the prevention and treatment of perioperative infectious complications in patients with benign prostatic hyperplasia.

Materials and Methods. In order to determine the effectiveness of antiseptics on the microflora of perioperative infectious complications, 90 patients were selected for the study. The species composition of the microflora of the obtained biological material in the perioperative period was studied. Microflora was isolated from the surface of the postoperative wound, from drainages and the surface of the urethral catheter. Using generally accepted microbiological methods, the sensitivity of the leading pathogens of the purulent-inflammatory process to antiseptics was studied. Quantitative indicators were processed statistically.

Results. The conditionally pathogenic microflora of the perioperative area and bacteriological analysis of urine culture in the perioperative period in patients with benign prostatic hyperplasia were characterized by heterogeneity, where the main share belonged to the representatives of gram-negative microflora (Acinetobacter baumannii, Pseudomonas aeruginosa) and enterobacteria (Escherichia coli, Klebsiella pneumoniae ss. Pneumoniae), while among gram-positive microflora, staphylococci (Staphylococcus aureus, Staphylococcus epidermitis and Staphylococcus haemolyticus) were observed. In a comparative analysis, patients who underwent transvesical prostatectomy had higher rates of microbial contamination compared to groups 2 and 3, who underwent vesical prostatectomy (p<0.05). This is explained by the possibility of infected urine entering the prostatic and vesical spaces through suprapubic bladder drains, which are installed before surgery.

Сonclusions. Laparoscopic retropubic prostatectomy allows for better treatment results and fewer postoperative complications than open retropubic prostatectomy. Preparations based on cationic surfactants have powerful bacteriostatic and bactericidal properties against staphylococci, gram-negative non-fermenting microorganisms, and enterobacteria. Further studies are needed to be able to recommend laparoscopic retrograde prostatectomy in the practice of urological clinics in Ukraine that have laparoscopic equipment.

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Published

2025-05-28

How to Cite

SHAPRYNSKYI, V. O., NAZARCHUK, O. A., GOROVYI, V. I., DOVHAN, I. I., BABINA, Y. M., & VERBA, M. A. (2025). THE EFFECT OF ANTISEPTICS ON THE MICROFLORA OF PERIOPERATIVE INFECTIOUS COMPLICATIONS IN PATIENTS WITH BENIGN PROSTATIC HYPERPLASIA. Hospital Surgery. Journal Named by L.Ya. Kovalchuk, (2), 16–24. https://doi.org/10.11603/2414-4533.2025.2.15378

Issue

No. 2 (2025)

Section

ORIGINAL INVESTIGATIONS

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Copyright (c) 2025 В. О. ШАПРИНСЬКИЙ, О. А. НАЗАРЧУК, В. І. ГОРОВИЙ, І. І. ДОВГАНЬ, Ю. М. БАБІНА, М. А. ВЕРБА

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