Safety and efficiency of simultaneous laparoscopic surgery in treatment of gallstone disease and surgical comorbidity

Authors

  • I. Ya. Dziubanovskyi І. Horbachevsky Ternopil State Medical University
  • M. M. Halei Volyn Regional Clinical Hospital
  • P. A. Gashchishyn Volyn Regional Clinical Hospital
  • I. P. Marchuk Volyn Regional Clinical Hospital

DOI:

https://doi.org/10.11603/2414-4533.2019.1.9914

Keywords:

surgery, cholecystectomy, gallstone disease, laparoscopy, simultaneous, stress

Abstract

The aim of the work: to find out the influence on physical health of the simultaneous laparoscopic operations in postoperative category of patients

Materials and Methods. Statistic data of 411 patients with gallstone disease with surgical comorbidity was used. For performance evaluation precise indicators were used, such as operative duration, hemorrhage volume, glycaemia, aldosterone and cortisol levels, oxygen blood saturation, creatinine and hemoglobin levels. Also Lee and ARISCAT scales were used. Results were used to make a database in Microsoft Office Excel 2010. Description of quantitative attributes was made based on the Shapiro-Wilk criterion, with the definition of the arithmetic mean (M) and standard deviation (S). Man-Whitney criteria or the U-criterion was used to compare the groups. For a wide comparison, the ANOVA method was used. The critical level of significance p in all calculations was detemined as 0.05.

Results and Discussion. After data processing increasing of average operative time was noted: (42±6) min. in group I and (51±9) min in group II. Regular monitoring the carbohydrates level in patients sufficiently helped to prevent subjective discomfort and weakness. Glycemic level didn’t have much difference and did not require insulin correction. Criterion of development of arterial hypotension was determined as decrease of the middle blood pressure up to 30 % from the initial or below 80 mmHg in the systolic phase, or deviation of the ST segment on the ECG.

References

https://reference.medscape.com/refarticle-srch/175667-overview

Asoh, T., Shirasaka, C., Uchido, I., Baldini G., Bagry H., & Carli F.

(1987). Effects of indomethacin on endocrine responses and nitrogen loss after surgery. Ann. Surg., 206, 770-776.

Smith, R., Kee, A., & Barrat S. (2008). Depth of anesthesia with desflu rane does not influence the endocrine methabolic response to

pelvic surgery. Acta Anaesth. Scand., 52, 99-105.

Beilin, B., Martin, F., & Shavit, Y. (2002). Multimodal analgesia and intravenous nutrition preserves total body protein following major upper gastrointestinal surgery. Reg.Anesth. PainMed., 27, 15-22.

Beilin, B., Bessler,,H., & Mayburd, E. (1989). Supression of natural killer cell activity by high dose narcotic anesthesia in rats. Brain Behave Immun., 3, 129-137.

Bent, J., Paterson, J., & Mashiter, K. (2003). Effects of preemptive analgesia on pain and cytokine production in the postoperative period. Anesthesiology, 98, 151-155.

Bromage, P., & Shibata, H. (1978). Effects of high dose fentanyl anaesthesia on the established metabolic and endocrine re sponse to surgery. Anaesthesia, 39, 19-23.

(1971). Influence of prolonged epidural block ade on blood sugar and cortisol responses to operation upon the upper part of the abdomen and thorax. Surg. Gynaecol. Obstetr. 21, 330-335.

Halliday, D., Cassuto, J., Nellgard, P., & Stage, L. (1997). Continuous epidural blockade arrests of postoperative decrease in muscle protein fractional synthetic rate in surgical patients. Anesthesiology, 86, 1033-1040.

Desborough, J., & Hall, G. (2001). The role of neuroinflammation and neuroimmune activation in persistent pain. Pain, 90, 1-6.

Desborough, J. (1989). Modification of the hormonal and metabolic response to surgery by narcotics and general anes thesia. Clin. Anaesthesiol., 3, 317-334.

Garlick, P., Burns, H., & Palmer, R. (2000). The stress response to trauma and surgery. Br. J. Anaesth., 85, 109-117.

Kehlet, H. (2006). The stress response to surgery: release mechanism and the role of pain relief. Acta Chir. Scand., (55), 22.

Kehlet, H. (1997). Multimodal approach to control postoperative pathophysiology and rehabilitation. Br. J. Anaesth., 78, 606-617.

Kehlet, H., & Wilmore, D. (1998). Modification of responses to surgery by neural blockade: clinical implications. Neural blockade in clinical anesthesia and management of pain. M. Cousins, P. Bridenbaugh (Eds.). Philadelphia, PA: Lippincott.

Published

2019-03-26

How to Cite

Dziubanovskyi, I. Y., Halei, M. M., Gashchishyn, P. A., & Marchuk, I. P. (2019). Safety and efficiency of simultaneous laparoscopic surgery in treatment of gallstone disease and surgical comorbidity. Hospital Surgery. Journal Named by L.Ya. Kovalchuk, (1), 62–68. https://doi.org/10.11603/2414-4533.2019.1.9914

Issue

Section

EXPERIENCE OF WORK