A new look at the issue of diagnostics of endogenous intoxication in patients with burn injury
DOI:
https://doi.org/10.11603/2414-4533.2019.1.9907Keywords:
burn injury, sepsis, method of fluorescence spectroscopyAbstract
The aim of the work: to diagnose the inflammatory changes in patients with burn injury in the framework of the method of fluorescence spectroscopy.
Materials and Methods. The clinical base of blood serum (BS) test for patients with burn injury was the Burn Department of the Communal City Clinical Hospital No.8 in Lviv. The experimental base was the Luminescence Laboratory of the Experimental Physics Department at the Ivan Franko Lviv National University. The subjects of the study were 48 samples of BS of 10 patients from 24 to 58 years old (7 males and 3 females) with burns of flame and boiling water of I-IIA-IIB degree in the total area from 18 to 45 % of the body surface, including head and neck.
Research and Discussion. Fluorescence spectra (FS) of BS of patients with burn injury, which are λ-like curves in the range of 300 nm <l <450 nm, were studied. The main indicators that were used for the analysis of FS of BS are the fluorescence intensity (If) and the position of the maximum of fluorescence band (lmax). FS studies began with the emergence of threatening signs of development of purulent-septic complications and were conducted in a dynamics with an interval of 3-8 days until recovery.
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