Аssessment of microhemodynamic by means of laser doppler floumetry in patients with chronic lower limb ischemia after transplantation of cord blood cells

Authors

  • D. В. DOMBROWSKYI ДВНЗ "Тернопільський державний медичний університет імені І.Я. Горбачевського МОЗ України"
  • V. V. SAVIN

DOI:

https://doi.org/10.11603/2414-4533.2016.1.5870

Abstract

Using laser doppler floumetry there was assessed the state of microhemodynamic and endothelial function in patients with chronic ischemia of the lower extremities against atherosclerotic lesions after transplantation of cord blood cells. Patients with symptoms of chronic lower limb ischemia on the background of atherosclerotic lesions performed transplantation of cord blood cells developed an original technique. In the pre- and postoperative period surveyed state microhemodynamic using laser Doppler floumetry. In patients with chronic limb ischemia when compared with standard parameters marked reduction capillary blood flow reserve occlusive test % and capillary blood flow reserve nitroglycerin test %: 119.2 ± 14.0 and 103.0 ± 45.0, against 200-400 and 442.4 ± 35.1 at norm. The value of background index microcirculation, Amax, AmaxN and index artery bypass grafting were greater in patients with chronic limb ischemia: 7.02 ± 1.04 units; 0.84 ± 0.12 units; 0.90 ± 0.11 units; and 2.53 ± 0.49 units 4.6-6.0 against units; 0.29 ± 0.04 units; 0.37 ± 0.07 and 1.13 ± 0.14 units, according to the regulations. When comparing the dynamics parameters LDF treatment after 1 and 3 months after transplantation of cord blood cells observed general improvement of microcirculation processes. Using cord blood cells to stimulate angiogenesis expands possibilities the successful treatment of patients with chronic ischemia of the lower extremities against atherosclerosis, as evidenced clinically and by means of laser Doppler floumetry.

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Published

2016-03-01

How to Cite

DOMBROWSKYI D. В., & SAVIN, V. V. (2016). Аssessment of microhemodynamic by means of laser doppler floumetry in patients with chronic lower limb ischemia after transplantation of cord blood cells. Hospital Surgery. Journal Named by L.Ya. Kovalchuk, (1). https://doi.org/10.11603/2414-4533.2016.1.5870

Issue

No. 1 (2016)

Section

ORIGINAL INVESTIGATIONS

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