ANALYSIS OF PERSONAL RESULTS OF SURGICAL TREATMENT OF PATIENTS WITH ACUTE CALCULOUS CHOLECYSTITIS USING LAPAROSCOPIC CHOLECYSTECTOMY

Authors

DOI:

https://doi.org/10.11603/2414-4533.2025.2.15270

Keywords:

laparoscopic cholecystectomy, diagnosis, treatment

Abstract

The aim of the work: to analyze the personal experience of treatment of acute calculous cholecystitis using laparoscopic cholecystectomy.

Materials and Мethods. A retrospective analysis of the treatment of 685 patients with uncomplicated acute calculous cholecystitis, who were hospitalized during 2021–2024, was conducted. Ultrasound examination of the abdominal organs were performed on Alpinion E-CUBE I7 and Esaote mylab seven devices. All laparoscopic cholecystectomies were performed under general anesthesia using the Karl Storz IMAGE 1 instrumentation and equipment. The effectiveness of treatment was assessed by the duration of hospital stay before and after surgery, the duration of surgery, the frequency of conversions, and intraoperative complications, as well as by complications of the postoperative period and postoperative mortality of patients. Statistical processing was performed using the SPSS 20.0 for Windows statistical software package.

Results. During the examination, the most characteristic diagnostic symptoms of acute calculous cholecystitis were: constant or paroxysmal pain in the right subcostal area in 100 % of patients; Murphy’s sign in 92.5 % of cases; increased C-reactive protein – 62.5 % of patients; increase the number of leukocyte – 97.8 % of patients. During a comprehensive examination, 87.4 % of patients were found to have a number of concomitant pathologies. The main method of visualization of the acute calculous cholecystitis was ultrasound, which was performed in 100 % of patients. The majority of surgical interventions were performed within 76 hours from the moment of admission to the hospital (78.8 %, р<0.001). The most frequent complications of acute calculous cholecystitis were: empyema of the gallbladder – 22.7 %, hydrops of the gallbladder – 12.5 %, local peritonitis – 13.8 %, paravesical abscess – 6.5 %, perforation of the gallbladder – 0.8 %.

Conclusions. A timely clinical examination was conducted that fully allowed us for the diagnosis of acute calculous cholecystitis and, as soon as possible, to determine indications for surgical treatment. Therefore, early laparoscopic cholecystectomy allows to reduce the traumatic nature of surgical intervention, the number of intra- and postoperative complications, and significantly reduce the duration of inpatient treatment and rehabilitation of patients.

References

Gallaher JR., Charles A. Acute Cholecystitis: A Review. JAMA. 2022; 327(10):965-75. DOI: 10.1001/jama.2022.2350. DOI: https://doi.org/10.1001/jama.2022.2350

Navarro SM, Chen S, Situ X, Corwin MT, Loehfelm T, Fananapazir G. Sonographic Assessment of Acute Versus Chronic Cholecystitis: An Ultrasound Probability Stratification Model. J Ultrasound Med. 2023; 42(6):1257-65. DOI: 10.1002/jum.16138. DOI: https://doi.org/10.1002/jum.16138

Pisano M, Ceresoli M, Cimbanassi S, Gurusamy K, Coccolini F, et al. 2017 WSES and SICG guidelines on acute calcolous cholecystitis in elderly population. World J Emerg Surg. 2019; 4:14:10. DOI: 10.1186/s13017-019-0224-7.

Okamoto Kohji, Suzuki K, Takada T, Strasberg SM, Asbun HJ, et al. Tokyo Guidelines 2018: flowchart for the management of acute cholecystitis. J Hepatobiliary Pancreat Sci. 2018; 25(1):55-72. DOI: 10.1002/jhbp.516. DOI: https://doi.org/10.1002/jhbp.516

Martínek L, Hoch J. Early cholecystectomy. Rozhl Chir. 2024; 103(8):294-98. DOI: 10.48095/ccrvch2024294. DOI: https://doi.org/10.48095/ccrvch2024294

Wael M, Seif M, Mourad M, Altabbaa H, Ibrahim IM, Elkeleny MR. Early Versus Delayed Laparoscopic Cholecystectomy, after Percutaneous Gall Bladder Drainage, for Grade II Acute Cholecystitis TG18 in Patients with Concomitant Cardiopulmonary Disease. J Laparoendosc Adv Surg Tech A. 2024; 34(12):1069-78. DOI: 10.1089/lap.2024.0233. DOI: https://doi.org/10.1089/lap.2024.0233

Gutt C, Schläfer S. Cholecystectomy in acute cholecystitis – a surgical emergency or elective in the next day’s program? Chirurgie (Heidelb). 2022; 93(6):535-41. DOI: 10.1007/s00104-022-01597-9. DOI: https://doi.org/10.1007/s00104-022-01597-9

Nassar A, Elshahat I, Forsyth K, Shaikh S, Ghazanfar M. Outcome of early cholecystectomy compared to percutaneous drainage of gallbladder and delayed cholecystectomy for patients with acute cholecystitis: systematic review and meta-analysis. HPB (Oxford). 2022; 24(10):1622-33. DOI: 10.1016/j.hpb.2022.04.010. DOI: https://doi.org/10.1016/j.hpb.2022.04.010

Köstenbauer JK, Gandy RC, Close J, Harvey L. Factors Affecting Early Cholecystectomy for Acute Cholecystitis in Older People – A Population-Based Study. World J Surg. 2023; 47(7):1704-10. DOI: 10.1007/s00268-023-06968-9. DOI: https://doi.org/10.1007/s00268-023-06968-9

Bundgaard NS, Bohm A, Hansted AK, Skovsen AP. Early laparoscopic cholecystectomy for acute cholecystitis is safe regardless of timing. Langenbecks Arch Surg. 2021; 406(7):2367-73. DOI: 10.1007/s00423-021-02229-2. DOI: https://doi.org/10.1007/s00423-021-02229-2

Memişoğlu E, Sarı R. Timing of cholecystectomy in recurrent attacks of acute cholecystitis. Ulus Travma Acil Cerrahi Derg. 2022; 28(4):508-12. DOI: 10.14744/tjtes.2022.81908. DOI: https://doi.org/10.14744/tjtes.2022.81908

Yuksekdag S, Bas G, Okan I, Karakelleoglu A, Alimoglu O, Akcakaya A, Sahin M. Timing of laparoscopic cholecystectomy in acute cholecystitis. Niger J Clin Pract. 2021; 24(2):156-60. DOI: 10.4103/njcp.njcp_138_20. DOI: https://doi.org/10.4103/njcp.njcp_138_20

Alenezi AT, Bin Jerais SA, Al Yami NMH, Alluhaida AA, Alharbi AK, Al Salamah FSJ, Assiri FFM, Tahir E Hayat Mohammed M, Alqahtani FMD, Otayf MM. Impact of Surgical Timing on Outcomes in Patients With Acute Cholecystitis: A Systematic Review. Cureus. 2024; 16(10):e72090. DOI: 10.7759/cureus.72090. DOI: https://doi.org/10.7759/cureus.72090

Ramia JM, Serradilla-Martín M, Villodre C, Rubio JJ, Rotellar F, Siriwardena AK, et al. International Delphi consensus on the management of percutaneous choleystostomy in acute cholecystitis (E-AHPBA, ANS, WSES societies). World J Emerg Surg. 2024; 19(1):32. DOI: 10.1186/s13017-024-00561-8. DOI: https://doi.org/10.1186/s13017-024-00561-8

Strohäker J, Sabrow J, Meier A, Königsrainer A, Ladurner R, Yurttas C. Primary admission to a surgical service facilitates early cholecystectomy in acute cholecystitis but does not influence patient outcome. Langenbecks Arch Surg. 2023; 408(1):225. DOI: 10.1007/s00423-023-02957-7. DOI: https://doi.org/10.1007/s00423-023-02957-7

Borzellino G, Khuri S, Pisano M, et al. Timing of early laparoscopic cholecystectomy for acute calculous cholecystitis: a meta-analysis of randomized clinical trials. World J Emerg Surg. 2021; 16:16. DOI: 10.1186/s13017-021-00360-5. DOI: https://doi.org/10.1186/s13017-021-00360-5

de’Angelis N, Catena F, Memeo R, Coccolini F, et al. 2020 WSES guidelines for the detection and management of bile duct injury during cholecystectomy. World J Emerg Surg. 2021; 16(1):30. DOI: 10.1186/s13017-021-00369-w. DOI: https://doi.org/10.1186/s13017-021-00369-w

Pisano M, Allievi N, Gurusamy K, Borzellino G, Cimbanassi S, et al. 2020 World Society of Emergency Surgery updated guidelines for the diagnosis and treatment of acute calculus cholecystitis. World J Emerg Surg. 2020; 15:61. DOI: 10. 1186/ s13017- 020- 00336-x. DOI: https://doi.org/10.1186/s13017-020-00336-x

Pisano M, Ceresoli M, Cimbanassi S, Gurusamy K, Coccolini F, et al. 2017 WSES and SICG guidelines on acute calcolous cholecystitis in elderly population. World J Emerg Surg. 2019 Mar. 4; 14:10. DOI: 10.1186/s13017-019-0224-7. DOI: https://doi.org/10.1186/s13017-019-0224-7

Yokoe M, Takada T, Strasberg SM, Solomkin JS, Mayumi T, et al. TG13 diagnostic criteria and severity grading of acute cholecystitis (with videos). J Hepatobiliary Pancreat Sci. 2013; 20:35-46. DOI: 10.1007/s00534-012-0568-9. DOI: https://doi.org/10.1007/s00534-012-0568-9

Yokoe M, Hata J, Takada T, Strasberg SM, Asbun HJ, et al. Tokyo Guidelines 2018: diagnostic criteria and severity grading of acute cholecystitis (with videos). J Hepatobiliary Pancreat Sci. 2018; 25(1):41-54. DOI: 10.1002/jhbp.515. DOI: https://doi.org/10.1002/jhbp.515

Panni RZ, Strasberg SM. Preoperative predictors of conversion as indicators of local inflammation in acute cholecystitis: strategies for future studies to develop quantitative predictors. J Hepatobiliary Pancreat Sci. 2018; 25(1):101-8. DOI: 10.1002/jhbp.493. DOI: https://doi.org/10.1002/jhbp.493

Djelil D, Regimbeau J-M, Pocard M. Challenging laparoscopic cholecystectomy for acute cholecystitis: When and how to convert. J Visc Surg. 2023; 160(2):134-42. DOI: 10.1016/j.jviscsurg.2022.09.008. DOI: https://doi.org/10.1016/j.jviscsurg.2022.09.008

Seshadri A, Peitzman AB. The difficult cholecystectomy: What you need to know. Trauma Acute Care Surg. 2024; 97(3):325-336. DOI: 10.1097/TA.0000000000004337. DOI: https://doi.org/10.1097/TA.0000000000004337

Published

2025-05-28

How to Cite

DEYKALO, I. M., OSADCHUK, D. V., GERASYMCHUK, P. O., & FIRA, D. B. (2025). ANALYSIS OF PERSONAL RESULTS OF SURGICAL TREATMENT OF PATIENTS WITH ACUTE CALCULOUS CHOLECYSTITIS USING LAPAROSCOPIC CHOLECYSTECTOMY. Hospital Surgery. Journal Named by L.Ya. Kovalchuk, (2), 75–82. https://doi.org/10.11603/2414-4533.2025.2.15270

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EXPERIENCE OF WORK