PREVALENCE OF COMORBID PATHOLOGY IN MALE PATIENTS WITH ISCHEMIC HEART DISEASE AT THE PLANNING STAGE OF MYOCARDIAL REVASCULARIZATION
DOI:
https://doi.org/10.11603/2414-4533.2025.1.15183Keywords:
comorbid pathology, Charlson comorbidity index, age characteristics, gender aspects, coronary artery bypass graftingAbstract
The aim of the work: to analyze the prevalence of comorbid conditions in male cardiac surgical patients with ischemic heart disease of different ages at the planning stage of myocardial revascularization.
Materials and Methods. The study included patients with ischemic heart disease submitted to coronary artery bypass grafting (n=3059). The average age of the patients was (58.8±0.9) years. The material for the study was anamnestic and diagnostic and treatment data of 3059 electronic medical records of male patients with ischemic heart disease for the period from 2015 to 2021. All patients included in the study were under dispensary observation at the State Institution «Amosov National Institute of Cardio-Vascular Surgery affiliated to National Academy of Medical Sciences of Ukraine» and at the municipal non-profit enterprise «Cherkasy Regional Cardiology Center of the Cherkasy Regional Council». To standardize approaches to assessing comorbidity, the Charlson Comorbidity Index (CCI) and the Charlson Comorbidity Index combined by age (CA-CCI) were determined.
Results. The analysis revealed the frequencies of the most common comorbid diseases in male patients with ischemic heart disease at the time of planning myocardial revascularization, which were: chronic heart failure – 84.9 %, myocardial infarction – 58.5 %, chronic kidney disease – 30.7 % and peripheral vascular disease – 22.6 %. Statistical differences were found in the frequencies of different age groups for: myocardial infarction, chronic heart failure, peripheral vascular disease, stroke, chronic lung disease, type II diabetes mellitus, chronic kidney disease and malignant neoplasms. It was found that the average number of diseases in one patient with ischemic heart disease was 2.7±0.3, variation range: 2–7. It was found that the highest SA-CCI was in senile patients – 6.7 and in elderly patients – 5.5.
Conclusions. As a result of the study, the frequencies of the most common comorbid diseases in male patients with coronary artery disease of different age groups were determined. It was determined that the average number of diseases in one male patient with coronary artery disease at the time of presentation for revascularization was 2.7±0.3. It was established that the average value of SCI was 3.1±0.3, and taking into account the age of the patients, SA-SCI increased to 4.6±0.4, which must be taken into account when planning the method of myocardial revascularization. A comprehensive assessment of the prevalence of comorbid diseases in male patients with coronary artery disease at the time of planning myocardial revascularization was carried out by determining SCI and SA-SCI, which allowed choosing a method taking into account the patient’s life expectancy.
References
Shchukina OS, Kovalʹ OA. Porivnyalʹna kharakterystyka khvorykh z hostrym koronarnym syndromom za danymy ukrayinsʹkykh ta yevropeysʹkykh reyestriv 2009–2015 rr.[Comparative characteristics of patients with acute coronary syndrome according to Ukrainian and European registries 2009–2015]. Medychna perspektyvy. 2017; ХХІІ;1:32-7. Ukrainian. DOI: https://doi.org/10.26641/2307-0404.2017.1.100871
Sobel BE. Coronary revascularization in patients with type 2 diabetes and results of the BARI 2D trial. Coron Artery Dis. 2010 May; 21(3):189-98. DOI: 10.1097/MCA.0b013e3283383ebe. DOI: https://doi.org/10.1097/MCA.0b013e3283383ebe
Farkouh ME, Domanski M, Dangas GD, Godoy LC, Mack MJ, Siami F S, et al. Long-Term Survival Following Multivessel Revascularization in Patients With Diabetes: The FREEDOM Follow-On Study. J Am Coll Cardiol. 2019 Feb.; 19;73(6):629-38. DOI: 10.1016/j.jacc.2018.11.001. DOI: https://doi.org/10.1016/j.jacc.2018.11.001
Arbel Y, Fuster V, Baber U, Hamza TH, Siami FS, Farkouh ME Incidence, determinants and impact of acute kidney injury in patients with diabetes mellitus and multivessel disease undergoing coronary revascularization: Results from the FREEDOM trial. Int J Cardiol. 2019 Oct.; 15;293:197-202. DOI: 10.1016/j.ijcard.2019.05.064. DOI: https://doi.org/10.1016/j.ijcard.2019.05.064
Pirillo A, Norata GD. The burden of hypercholesterolemia and ischemic heart disease in an ageing world. Pharmacol Res. 2023; 193:106814. DOI: 10.1016/j.phrs.2023.106814. DOI: https://doi.org/10.1016/j.phrs.2023.106814
Shanmugam VB, Harper R, Meredith I, Malaiapan Y, Psaltis PJ. An overview of PCI in the very elderly. J Geriatr Cardiol. 2015 Mar; 12(2):174-84. DOI: 10.11909/j.issn.1671-5411.2015.02.012
Shemesh E, Zafrir B. Coronary angiography in the very old: impact of diabetes on long-term revascularization and mortality. J Geriatr Cardiol. 2019 Jan.; 16(1):27-32. DOI: 10.11909/j.issn.1671-5411.2019.01.006.
Edwards FH, Ferraris VA, Shahian DM, Peterson E, Furnary AP, Haan CK, Bridges CR. Society of Thoracic Surgeons. Gender-specific practice guidelines for coronary artery bypass surgery: perioperative management. Ann Thorac Surg. 2005 Jun.; 79(6):2189-94. DOI: 10.1016/j.athoracsur.2005.02.065. DOI: https://doi.org/10.1016/j.athoracsur.2005.02.065
Harik L, Perezgrovas-Olaria R, Jr Soletti G, Dimagli A, Alzghari T, An KR, et al. Sex differences in coronary artery bypass graft surgery outcomes: a narrative review. J Thorac Dis. 2023 Sep.; 28;15(9):5041-054. DOI: 10.21037/jtd-23-294. DOI: https://doi.org/10.21037/jtd-23-294
Quan H, Sundararajan V, Halfon P, et al. Coding algorithms for defining comorbidities in ICD-9-CM and ICD-10 administrative data. Med Care. 2005; 43(11):1130-139. DOI: 10.1097/01.mlr.0000182534.19832.83. DOI: https://doi.org/10.1097/01.mlr.0000182534.19832.83
Moroz HZ, Hidzynsʹka IM, Lasytsya TS. Kompleksna otsinka komorbidnosti v klinichniy praktytsi: metodychni pidkhody ta praktychne vykorystannya [Comprehensive assessment of comorbidity in clinical practice: methodological approaches and practical use]. Klinichna ta profilaktychna medytsyna. 2021; 2(16):32-8. DOI: 10.31612/2616-4868.2(16).2021.04. Ukrainian. DOI: https://doi.org/10.31612/2616-4868.2(16).2021.04
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