PREDICTORS OF THE FORMATION OF INTRA-ABDOMINAL HYPERTENSION SYNDROME IN BLUNT ABDOMINAL TRAUMA
DOI:
https://doi.org/10.11603/2414-4533.2025.1.15180Keywords:
infusion therapy, intra-abdominal hypertension, natriuretic peptide, abdominal perfusion pressureAbstract
The aim of the work: to determine the predictors of intra-abdominal hypertension syndrome formation in patients with polytrauma and combined trauma complicated by blunt trauma of abdominal organs.
Materials and Methods. The study involved 28 patients with polytrauma and combined trauma, who were divided into groups depending on the level of intra-abdominal hypertension. Distribution took place at the end of the first day after the initial stabilization of the patients. Intra-abdominal pressure was measured in the bladder according to the recommendations of the World Society for the Study of Intra-Abdominal Hypertension and Abdominal Compartment Syndrome (WSACS, 2013). The criterion for the development of intra-abdominal hypertension was the determination of increased intra-abdominal pressure in two consecutive measurements within 6 hours. Statistical data processing was carried out using Windows 11 Microsoft Office Excel formulas with the determination of the Student-t test, the calculation of the p-error. NT-proBNP levels were determined using Exdia Precision Biosensor Inc. test systems (normal level is less than 125 pg/ml).
Results. Data analysis revealed a significant difference in the levels of intra-abdominal pressure in patients of the studied groups on the 24th ((7.73±2.13) mm Hg vs. (16.4±5.0) mm Hg, p≤0.05) and on the 30th ((7.6±1.99) mm Hg versus (13.08±2.98) mm Hg, p≤0.05) hours. Also, significant differences were found when analyzing the level of platelets at the end of the first day of treatment ((217.67±128.44) T/l in the group of patients without intra-abdominal hypertension versus (180.25±93.96) T/l in the group of patients with intra-abdominal hypertension, p≤0.01). At the limit of reliability (p=0.057), the volumes of blood preparations were used, so in the group without the formation of the syndrome of intra-abdominal hypertension, the volume of transfusions on the first day was (549.87±448.42) ml against (982.92±686.59) ml in patients with a developed syndrome of intra-abdominal hypertension.
Conclusions. Laboratory and clinical markers identified in patients with ICH syndrome in blunt trauma were a decrease in the level of platelets (p≤0.01) and the need for volume blood transfusions, but this indicator was at the limit of confidence (p=0.057).
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