DAMAGE TO THE EXTRAHEPATIC DUCTS. A MODERN VIEW OF THE PROBLEM
DOI:
https://doi.org/10.11603/2414-4533.2024.4.15064Keywords:
biliary trauma, hepaticojejunostomy, vasculobiliary traumaAbstract
The aim of the work: to study of the causes, risks, prevention and treatment of injuries of the extrahepatic bile ducts, in particular during cholecystectomy, as well as analysis of modern methods of intraoperative diagnostics and restoration of the integrity of the biliary tree.
Materials and Methods. A literature analysis of data on the frequency of biliary injuries, modern methods of surgical interventions (classical and minimally invasive), methods of intraoperative visualization (cholangiography, fluorescent visualization) and methods of reconstruction (hepaticojejunostomy) was used.
Results. Biliary injuries are serious complications that often occur during laparoscopic cholecystectomy. This is due to the peculiarities of the technique and the difficulty of identifying anatomical structures in the hepatoduodenal zone. The analysis conducted indicates the effectiveness of the use of intraoperative visualization methods, such as cholangiography, which can help reduce the risk of bile duct injury by improving visualization of the anatomy. For the treatment of minor injuries, special attention is paid to endoscopic retrograde cholangiopancreatography (ERCP), which is a diagnostic and therapeutic method. It allows to ensure the outflow of bile, eliminate small defects and reduce postoperative complications. At the same time, the experience of the surgeon plays a key role in reducing the frequency of biliary injuries, as confirmed by the learning curve: the risk is significantly reduced after the first 100–200 operations performed. Standardization of the approach to diagnosis and treatment is ensured by the use of classifications such as Bismuth and Strasberg, which systematize the types of injuries depending on their anatomical localization and degree of damage. This allows doctors to make optimal clinical decisions faster and reduce the frequency of complications.
Conclusions. Biliary injury is a serious problem with high risks for the patient. Modern methods of intraoperative imaging are important for minimizing injuries. Patients with serious injuries should be referred to specialized centers. Minimally invasive treatment techniques are a priority.
References
Abdel Rafee A, El-Shobari M, Askar W, Sultan AM, El Nakeeb A. Long-term follow-up of 120 patients after hepaticojejunostomy for treatment of post-cholecystectomy bile duct injuries: A retrospective cohort study. Int J Surg. 2015; 18:205-10. DOI: 10.1016/j.ijsu.2015.05.004. DOI: https://doi.org/10.1016/j.ijsu.2015.05.004
Aerts R, Penninckx F. The burden of gallstone disease in Europe. Alimentary Pharmacology & Therapeutics. 2003; 18:49-53. DOI: https://doi.org/10.1046/j.0953-0673.2003.01721.x
Brunner M, Golcher H, Krautz C, Kersting S, Weber GF, Grützmann R. Continuous or interrupted suture technique for hepaticojejunostomy during pancreatoduodenectomy (HEKTIK trial): study protocol of a randomized controlled multicenter trial. Trials. 2022; 6,23(1):467. DOI: 10.1186/s13063-022-06427-1. DOI: https://doi.org/10.1186/s13063-022-06427-1
Bismuth H, Majno PE. (), Biliary Strictures: Classification Based on the Principles of Surgical Treatment. World J. Surg. 2001; 25:1241-44. DOI: 10.1007/s00268-001-0102-8. DOI: https://doi.org/10.1007/s00268-001-0102-8
Booij KAC, Coelen RJ, de Reuver PR, Besselink MG, van Delden OM, Rauws EA, Busch OR, van Gulik TM, Gouma DJ. Long-term follow-up and risk factors for strictures after hepaticojejunostomy for bile duct injury: An analysis of surgical and percutaneous treatment in a tertiary center. Surgery. 2018; 163(5):1121-27. DOI: 10.1016/j.surg.2018.01.003. DOI: https://doi.org/10.1016/j.surg.2018.01.003
Chehade M, Kakala B, Sinclair JL, Pang T, Al Asady R, Richardson A, Pleass H, Lam V, Johnston E, Yuen L, Hollands M.- Intraoperative detection of aberrant biliary anatomy via intraoperative cholangiography during laparoscopic cholecystectomy. ANZ J Surg. 2019; 89(7-8):889-94. DOI: 10.1111/ans.15267. DOI: https://doi.org/10.1111/ans.15267
de’Angelis N, Catena F, Memeo R. et al. WSES guidelines for the detection and management of bile duct injury during cholecystectomy. World J Emerg Surg. 2020; 16:30. DOI: 10.1186/s13017-021-00369-w. DOI: https://doi.org/10.1186/s13017-021-00369-w
El-Dhuwaib Y, Slavin J, Corless DJ, Begaj I, Durkin D, Deakin M. Bile duct reconstruction following laparoscopic cholecystectomy in England. Surg Endosc. 2016; 30(8): 3516-25. DOI: 10.1007/s00464-015-4641-8. DOI: https://doi.org/10.1007/s00464-015-4641-8
Jason A Kemp, Randall S Zuckerman, Samuel RG Finlayson. Trends in Adoption of Laparoscopic Cholecystectomy in Rural Versus Urban Hospitals. Journal of the American College of Surgeons. 2008; 206(1):28-32. DOI: 10.1016/j.jamcollsurg.2007.06.289. DOI: https://doi.org/10.1016/j.jamcollsurg.2007.06.289
Javed A, Shashikiran BD, Aravinda PS, Agarwal AK. Laparoscopic versus open surgery for the management of post-cholecystectomy benign biliary strictures. Surg Endosc. 2021; 35(3):1254-63. DOI: 10.1007/s00464-020-07496-6. DOI: https://doi.org/10.1007/s00464-020-07496-6
Komatsu M, Yokoyama N, Katada T, et al. Learning curve for the surgical time of laparoscopic cholecystectomy performed by surgical trainees using the three-port method: how many cases are needed for stabilization? Surg Endosc. 2023; 37:1252-61. DOI: 10.1007/s00464-022-09666-0. DOI: https://doi.org/10.1007/s00464-022-09666-0
Lai W, Yang J, Xu N, Chen JH, Yang C, Yao HH. Surgical strategies for Mirizzi syndrome: A ten-year single center experience. World J Gastrointest Surg. 2022; 14(2):107-19. DOI: 10.4240/wjgs.v14.i2.107. DOI: https://doi.org/10.4240/wjgs.v14.i2.107
Loh AYH, Chean CS, Durkin D, Bhatt A, Athwal TS. Short and long term outcomes of laparoscopic fenestrating or reconstituting subtotal cholecystectomy versus laparoscopic total cholecystectomy in the management of acute cholecystitis. HPB (Oxford). 2022; 24(5):691-99. DOI: 10.1016/j.hpb.2021.09.018. DOI: https://doi.org/10.1016/j.hpb.2021.09.018
Moore MJ, Bennett CL. The learning curve for laparoscopic cholecystectomy. The Southern Surgeons Club. Am J Surg. 1995; 170(1):55-9. DOI: 10.1016/s0002-9610(99)80252-9. DOI: https://doi.org/10.1016/S0002-9610(99)80252-9
Miyano G, Koyama M, Miyake H, Kaneshiro M, Morita K, Nakajima H, Yamoto M, Nouso H, Fukumoto K, Urushihara N. Comparison of laparoscopic hepaticojejunostomy and open hepaticojejunostomy. Can stenosis of the hilar hepatic duct affect postoperative outcome? Asian J Endosc Surg. 2017; 10(3):295-300. DOI: 10.1111/ases.12358. DOI: https://doi.org/10.1111/ases.12358
Ortenzi M, Corallino D, Botteri E, Balla A, Arezzo A, Sartori A, Reddavid R, Montori G, Guerrieri M, Williams S, Podda M. SCOTCH Study Collaborative Group. Safety of laparoscopic cholecystectomy performed by trainee surgeons with different cholangiographic techniques (SCOTCH): a prospective non-randomized trial on the impact of fluorescent cholangiography during laparoscopic cholecystectomy performed by trainees. Surg Endosc. 2024; 38(2):1045-58. DOI: 10.1007/s00464-023-10613-w. DOI: https://doi.org/10.1007/s00464-023-10613-w
Olmez A, Hatipoglu S, Itik V, Kotan C. T-tube bridging for the management of biliary tree injuries. Am J Case Rep. 2012; 13:247-49. DOI: 10.12659/AJCR.883499. DOI: https://doi.org/10.12659/AJCR.883499
Pesce A, Fabbri N, Feo CV. Vascular injury during laparoscopic cholecystectomy: An often-overlooked complication. World J Gastrointest Surg. 2023; 15(3):338-45. DOI: 10.4240/wjgs.v15.i3.338. DOI: https://doi.org/10.4240/wjgs.v15.i3.338
Perera MT, Silva MA, Hegab B, Muralidharan V, Bramhall SR, Mayer AD, Buckels JA, Mirza DF. Specialist early and immediate repair of post-laparoscopic cholecystectomy bile duct injuries is associated with an improved long-term outcome. Ann Surg. 2011; 253(3):553-60. DOI: 10.1097/SLA.0b013e318208fad3. DOI: https://doi.org/10.1097/SLA.0b013e318208fad3
Reitano E, de'Angelis N, Schembari E, Carrà MC, Francone E, Gentilli S, La Greca G. Learning curve for laparoscopic cholecystectomy has not been defined: A systematic review. ANZ J Surg. 2021; 91(9): 554-60. DOI: 10.1111/ans.17021. DOI: https://doi.org/10.1111/ans.17021
Strasberg S. A perspective on the critical view of safety in laparoscopic cholecystectomy. Annals of Laparoscopic and Endoscopic Surgery. 2017; 2(5). Available from: https://ales.amegroups.org/article/view/3940. DOI: https://doi.org/10.21037/ales.2017.04.08
Sgaramella LI, Gurrado A, Pasculli A, de Angelis N, Memeo R, Prete FP, et al. The critical view of safety during laparoscopic cholecystectomy: Strasberg Yes or No? An Italian multicentre study. Surg Endosc. 2021; 35:3698-708. DOI: 10.1007/s00464-020-07852-6. DOI: https://doi.org/10.1007/s00464-020-07852-6
Stewart L, Way LW. Bile duct injuries during laparoscopic cholecystectomy. Factors that influence the results of treatment. Arch Surg. 1995; 130(10):1123-28. DOI: 10.1001/archsurg.1995.01430100101019. DOI: https://doi.org/10.1001/archsurg.1995.01430100101019
Sbuelz F, Oppici D, Scotti A, Berardi G, Gugliemo N, Colasanti M, Levi Sandri G, Ettorre G. Bile duct injuries management: the experience of a high volume liver surgery centre. Digestive Medicine Research. 2020; 3(0). Available from: https:// dmr.amegroups.org/article/view/6851. DOI: https://doi.org/10.21037/dmr-20-90
Schreuder AM, Nunez Vas BC, Booij KAC, van Dieren S, Besselink MG, Busch OR, et al. Optimal timing for surgical reconstruction of bile duct injury: meta-analysis. BJS Open. 2020; 4(5):776-86. DOI: 10.1002/bjs5.50321. DOI: https://doi.org/10.1002/bjs5.50321
Tornqvist B, Stromberg C, Akre O, Enochsson L, Nilsson M. Selective intraoperative cholangiography and risk of bile duct injury during cholecystectomy. Br Surg. J. 2015; 102(8):952-58. DOI: 10.1002/bjs.9832. DOI: https://doi.org/10.1002/bjs.9832
Van Dijk AH, Donkervoort SC, Lameris W, de Vries E, Eijsbouts QAJ, Vrouenraets BC, Busch OR, Boermeester MA, de Reuver PR. Short- and Long-Term Outcomes after a Reconstituting and Fenestrating Subtotal Cholecystectomy. J Am Coll Surg. 2017; 225(3):371-79. DOI: https://doi.org/10.1016/j.jamcollsurg.2017.05.016
Voitk AJ, Tsao SG, Ignatius S. The tail of the learning curve for laparoscopic cholecystectomy. Am J Surg. 2001; 182(3):250-53. DOI: 10.1016/s0002-9610(01)00699-7. DOI: https://doi.org/10.1016/S0002-9610(01)00699-7
Wang Z, Yu L, Wang W, Xia J, Li D, Lu Y, Wang B. Therapeutic strategies of iatrogenic portal vein injury after cholecystectomy. J Surg Res. 2013; 185(2):934-39. DOI: 10.1016/j.jss.2013.06.032. DOI: https://doi.org/10.1016/j.jss.2013.06.032
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