A CLINICAL CASE REPORT OF SECONDARY ANGIOSARCOMA OF THE BREAST IN A MALE

Authors

DOI:

https://doi.org/10.11603/2414-4533.2024.2.14858

Keywords:

breast, angiosarcoma, diagnosis, radiation therapy, surgical treatment

Abstract

The aim of the work: to describe a rare clinical case of secondary angiosarcoma of the breast in a man.

Results. The incidence of breast sarcoma among sarcomas of all localizations is 2.0%, and among all malignant breast tumors – less than 1% of all cases. Cases of breast sarcoma in males are rare. Therefore, each described case is interesting for study. Secondary angiosarcomas arise, as a rule, on the basis of lymphostasis after radiation therapy or surgical treatment of cancer (most often – breast cancer). The report describes a clinical case of secondary angiosarcoma of the breast in a male; the tumor arose 8 years after an axillary lymphadenectomy due to melanoma. The significance of various diagnostic methods is shown.

References

Lucani G, Cappella A, Bortul M, Stacul G, Scarabeo F, Procaccini E, Galimberti V. Secondary breast angiosarcoma: A multicentre retrospective survey by the national Italian association of Breast Surgeons (ANISC). Breast. 2019; 45:56-60. DOI: 10.1016/j.breast.2019.02.011.

Ely Cheikh T, Hamza K, Hicham B, Fatiha EM, Hajar EO, Mustapha B, Mohamed E, Mohamed E. Leiomyosarcoma of the male breast: case report. Ann Med Surg (Lond). 2021; 67:102495. DOI: 10.1016/j.amsu.2021.102495.

Radu I, Scripcariu V, Panuța A, Rusu A, Afrăsânie VA, Cojocaru E, Aniței MG, Alexa-Stratulat T, Terinte C, Șerban CF, Gafton B. Breast sarcomas-how different are they from breast carcinomas? clinical, pathological, imaging and treatment insights. Diagnostics (Basel). 2023; 13(8):1370. DOI: 10.3390/diagnostics13081370.

An R, Men XJ, Ni XH, Wang WT, Wang CL. Angiosarcoma of the breast: A review. Heliyon. 2024; 10(3):e24413. DOI: 10.1016/j.heliyon.2024.e24413.

Esposito E, Avino F, di Giacomo R, Donzelli I, Marone U, Melucci MT, Rinaldo C, Ruffolo F, Saponara R, Siani C, Tortoriello R, Botti G, Rinaldo M, Fucito A. Angiosarcoma of the breast, the unknown-a review of the current literature. Transl Cancer Res. 2019; 8(Suppl5):S510-S517. DOI: 10.21037/tcr.2019.07.38.

von Mehren M, Kane JM, Agulnik M, Bui MM, Carr-Ascher J, Choy E, Connelly M, Dry S, Ganjoo KN, Gonzalez RJ, Holder A, Homsi J, Keedy V, Kelly CM, Kim E, Liebner D, McCarter M, McGarry SV, Mesko NW, Meyer C, Pappo AS, Parkes AM, Petersen IA, Pollack SM, Poppe M, Riedel RF, Schuetze S, Shabason J, Sicklick JK, Spraker MB, Zimel M, Hang LE, Sundar H, Bergman MA. Soft Tissue Sarcoma, Version 2.2022, NCCN Clinical Practice Guidelines in Oncology. J Natl Compr Canc Netw. 2022; 20(7):815-833. DOI: 10.6004/jnccn.2022.0035.

Tsapralis N, Vlachogiorgos A, Pham H, Mowatt D. Nothing is impossible: radiation induced angiosarcoma of breast in a male patient. J Surg Case Rep. 2019; 2019(5):rjz158. DOI: 10.1093/jscr/rjz158.

Chikarmane SA, Gombos EC, Jagadeesan J, Raut C, Jagannathan JP. MRI findings of radiation-associated angiosarcoma of the breast (RAS). J Magn Reson Imaging. 2015; 42(3):763-70. DOI: 10.1002/jmri.24822.

Bentley H, Roberts J, Hayes M, Wilson C, Simmons C, Nichol A, Smrke A, Martin T. The role of imaging in the diagnosis of primary and secondary breast angiosarcoma: twenty-five-year experience of a provincial cancer institution. Clin Breast Cancer. 2023; (2):e45-e53. DOI: 10.1016/j.clbc.2022.11.003.

Jackson KM, Grumley JG. Radiation-induced breast angiosarcoma: updates on a rare disease. Current Breast Cancer Reports. 2024; 16(2):177-184. DOI: 10.1007/s12609-024-00542-5

Yang OO, Lan T, He JL, Xu HB, Hao L, Shu C, Hu ZJ, Luo H. Magnetic resonance imaging and contrast-enhanced ultrasound findings of a recurrent primary breast angiosarcoma: A case report. Medicine (Baltimore). 2021; 100(5):e24625. DOI:10.1097/MD.0000000000024625.

Yan M, Gilmore H, Bomeisl P, Harbhajanka A. Clinicopathologic and immunohistochemical study of breast angiosarcoma. Ann Diagn Pathol. 2021; 54:151795. DOI: 10.1016/j.anndiagpath.2021.151795.

Li J, Li Y, Wang Y, Li Z, Zhang H, Gao Y, Tan J. Clinicopathological characteristics and survival outcomes in patients with angiosarcoma of breast. Cancer Med. 2023; 12(12):13397-13407. DOI: 10.1002/cam4.6042.

Ginter PS, McIntire PJ, Irshaid LI, Liu YF, Shin SJ. Angiomatosis of the breast: a clinicopathological and immunophenotypical characterisation of seven cases. J. Clin. Pathol. 2019; 72(9): 597-602, DOI: 10.1136/jclinpath-2019-205821

Sullivan HC, Edgar MA, Cohen C, Kovach CK, HooKim K, Reid MD. The utility of ERG, CD31 and CD34 in the cytological diagnosis of angiosarcoma: an analysis of 25 cases. J Clin Pathol. 2015; 68(1):44-50. DOI: 10.1136/jclinpath-2014-202629.

An R, Men XJ, Ni XH, Wang WT, Wang CL. Angiosarcoma of the breast: A review. Heliyon. 2024; 10(3):e24413. DOI: 10.1016/j.heliyon.2024.e24413.

Herb J, Maduekwe UN, Goel N, Rosenberger LH, Spanheimer PM. Does Angiosarcoma of the Breast Need Nodal Staging? J Am Coll Surg. 2022; 234(5):774-782. DOI: 10.1097/XCS.0000000000000131.

Gutkin PM, Ganjoo KN, Lohman M, von Eyben R, Charville GW, Nazerali RS, Dirbas FM, Horst KC. Angiosarcoma of the breast: management and outcomes. Am J Clin Oncol. 2020; 43(11):820-825. DOI: 10.1097/COC.0000000000000753.

Singh R, Chufal KS, Pahuja AK, Suresh T, Chowdhary RL, Ahmad I. Primary angiosarcoma of the breast: a radiation oncologist's perspective with a concise review of the literature. BMJ Case Rep. 2019;12(7):e227036. DOI: 10.1136/bcr-2018-227036.

Thorpe CS, Niska JR, Brunnhoelzl DC, McGee LA, Kesslering CM, Hartsell WF, Vargas CE. First report of proton beam therapy for breast angiosarcoma from the prospective PCG registry. Acta Oncol. 2018; 57(7):992-994. DOI: 10.1080/0284186X.2017.1423179.

Bendavid JJ, Modesto A. Radiation therapy and antiangiogenic therapy: opportunities and challenges. Cancer Radiother., 26 (6–7) (2022), pp. 962-967. DOI: 10.1016/j.canrad.2022.06.

Florou V, Rosenberg AE, Wieder E, Komanduri KV, Kolonias D, Uduman M, Castle JC, Buell JS, Trent JC, Wilky BA. Angiosarcoma patients treated with immune checkpoint inhibitors: a case series of seven patients from a single institution. J Immunother Cancer. 2019; 7(1):213. DOI: 10.1186/s40425-019-0689-7.

Kollár A, Jones RL, Stacchiotti S, Gelderblom H, Guida M, Grignani G, Steeghs N, Safwat A, Katz D, Duffaud F, Sleijfer S, van der Graaf WT, Touati N, Litière S, Marreaud S, Gronchi A, Kasper B. Pazopanib in advanced vascular sarcomas: an EORTC Soft Tissue and Bone Sarcoma Group (STBSG) retrospective analysis. Acta Oncol. 2017; 56(1):88-92. DOI: 10.1080/0284186X.2016.1234068.

Published

2024-06-28

How to Cite

NITEFOR, L. V. (2024). A CLINICAL CASE REPORT OF SECONDARY ANGIOSARCOMA OF THE BREAST IN A MALE. Hospital Surgery. Journal Named by L.Ya. Kovalchuk, (2), 149–154. https://doi.org/10.11603/2414-4533.2024.2.14858

Issue

Section

CASE REPORT