Histologic analysis of the stomach after gastric arteries embolization in an experiment

Authors

  • A. M. PRODAN I. Horbachevsky Ternopil National Medical University
  • T. K. GOLOVATA I. Horbachevsky Ternopil National Medical University

DOI:

https://doi.org/10.11603/2414-4533.2023.4.14345

Keywords:

embolization of the arteries of the stomach, morphological changes of the stomach

Abstract

The aim of the work: to evaluate in an experiment the morphological changes of different parts of the stomach after embolization of its arteries.

Materials and Methods. Bariatric embolization of gastric arteries were performed in 10 pigs of the Vietnamese breed aged 4–5 months, which were simulated obesity with a high-fat diet for 2 months. The embolization technique included superselective bariatric embolization of the left gastric and gastroesophageal artery with emboli of 300 μm. Morphological examination was performed 3 weeks after surgery. Microscopic evaluation and photofixation of histopreparations of different parts of the stomach, stained with hematoxylin-eosin, was carried out with the help of a Nikon Eclipse Ci-E laboratory grade trinocular microscope with 10x, 20x and 40x planachromat lenses to identify ischemic and destructive changes in the organ and their severity.

Results and Discussion. Microscopically, we examined biopsies of the mucous membrane of different parts of the stomach – cardiac, fundal, body and antral, which was dictated by their structural and functional variability and features of blood supply. According to the results of microscopic analysis of the mucous membrane of different parts of the stomach after arterial embolization, two types of morphological state of its mucous membrane were established. In the cardiac and antral departments, the changes were characterized mainly by moderate desquamated changes and increased mucus formation; in the fundus and body of the stomach - superficial and deep erosion associated with hemorrhages and an inflammatory reaction.

References

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Published

2023-12-28

How to Cite

PRODAN, A. M., & GOLOVATA, T. K. (2023). Histologic analysis of the stomach after gastric arteries embolization in an experiment. Hospital Surgery. Journal Named by L.Ya. Kovalchuk, (4), 35–38. https://doi.org/10.11603/2414-4533.2023.4.14345

Issue

No. 4 (2023)

Section

EXPERIMENTAL INVESTIGATIONS

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Copyright (c) 2023 А. М. ПРОДАН, Т. К. ГОЛОВАТА

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