Clinical case of diagnosis and surgical treatment of malignant phyllodes tumor of the breast

Authors

  • L. V. Nitefor KNP "Ternopil Regional Clinical Oncology Dispensary" TOR
  • I. Y. Halaichuk KNP "Ternopil Regional Clinical Oncology Dispensary" TOR
  • O. R. Tumanova KNP "Ternopil Regional Clinical Oncology Dispensary" TOR
  • O. A. Miklashevska KNP "Ternopil Regional Clinical Oncology Dispensary" TOR
  • O. S. Karashivska KNP "Ternopil Regional Clinical Oncology Dispensary" TOR
  • T. Yu. Uglyar KNP "Ternopil Regional Clinical Oncology Dispensary" TOR
  • Yu. V. Uglyar KNP "Ternopil Regional Clinical Oncology Dispensary" TOR

DOI:

https://doi.org/10.11603/2414-4533.2023.2.13997

Keywords:

phyllodes tumors, surgical treatment, resection margins, adjuvant therapy

Abstract

The report describes a clinical case of diagnosis and successful surgical treatment of a patient with a giant-sized phyllodes tumor of the breast.

References

Adam, M. J., Bendifallah, S., Kalhorpour, N., Cohen-Steiner, C., Ropars, L., Mahmood, A., ... & Lavoue, V. (2018). Time to revise classification of phyllodes tumors of breast? Results of a French multicentric study. European Journal of Surgical Oncology, 44(11), 1743-1749. DOI: 10.1016/j.ejso.2018.08.007. [PubMed] [CrossRef] [Google Scholar]

Zhou, Z.R., Wang, C.C., Yang, Z.Z., Yu, X.L., & Guo, X.M. (2016). Phyllodes tumors of the breast: diagnosis, treatment and prognostic factors related to recurrence. Journal of Thoracic Disease, 8(11), 3361.

Shubham, S., Ahuja, A., & Bhardwaj, M. (2019). Immunohistochemical expression of Ki-67, p53, and CD10 in phyllodes tumor and their correlation with its histological grade. Journal of Laboratory Physicians, 11(04), 330-334. DOI: 10.4103/JLP.JLP_106_19. PMID: 31929699;PMCID:MC6943865.

Warrier, S., Hwang, S.Y., Gibbings, K., Carmalt, H., & O’Toole, S. (2015). Phyllodes tumour with heterologous sarcomatous differentiation: Case series with literature review. International journal of surgery case reports, 11, 91-94.

Qian, Y., Quan, M.L., Ogilvi, T., & Bouchard-Fortier, A. (2018). Surgical management of benign phyllodes tumours of the breast: Is wide local excision really necessary?. Canadian Journal of Surgery, 61(6), 430. DOI: 10.1503/cjs.017617.

Chen, C., Tsang, J. Y., Tse, G., & Kwong, A. (2018). Mammary phyllodes tumour: a 15-year multicentre clinical review. Journal of clinical pathology, 71(6), 493-497. DOI: 10.1136/jclinpath-2017-204827. [PubMed] [CrossRef] [Google Scholar]

Gutnik, L., Ren, Y., Thomas, S. M., Plichta, J. K., Greenup, R. A., Fayanju, O. M., ... & Rosenberger, L. H. (2022). Malignant phyllodes tumor and primary breast sarcoma; distinct rare tumors of the breast. Journal of Surgical Oncology, 125(6), 947-957. DOI: 10.1002/jso.26820.

Spitaleri, G., Toesca, A., Botteri, E., Bottiglieri, L., Rotmensz, N., Boselli, S., ... & De Pas, T. (2013). Breast phyllodes tumor: a review of literature and a single center retrospective series analysis. Critical reviews in oncology/hematology, 88(2), 427-436. DOI: 10.1016/j.critrevonc.2013.06.005.

Peneş, N.O., Pop, A.L., Borş, R.G., & Varlas, V.N. (2021). Large borderline phyllodes breast tumor related to histopathology, diagnosis, and treatment management–case report. Romanian Journal of Morphology and Embryology, 62(1), 283. DOI:10.47162/RJME.62.1.30.PMID: 34609433

Peneş, N.O., Pop, A.L., Borş, R.G., & Varlas, V.N. (2021). Large borderline phyllodes breast tumor related to histopathology, diagnosis, and treatment management–case report. Romanian Journal of Morphology and Embryology, 62(1), 283. DOI: 10.1016/j.ijscr.2018.10.038. [PMC free article] [PubMed] [CrossRef] [Google Scholar]

Center MAC (2021) Phyllodes tumor. https://www.mdanderson.org/content/dam/mdanderson/documents/for-physicians/algorithms/cancer-treatment/ca-treatment-phyllodes-web-algorithm.pdf

Sars, C., Sackey, H., Frisell, J., Dickman, P.W., Karlsson, F., Kindts, I., ... & Lindqvist, E.K. (2023). Current clinical practice in the management of phyllodes tumors of the breast: an international cross-sectional study among surgeons and oncologists. Breast cancer research and treatment, 199(2), 293-304. https://doi.org/10.1007/s10549-023-06896-1

Tan, B. Y., Acs, G., Apple, S. K., Badve, S., Bleiweiss, I. J., Brogi, E., ... & Tan, P. H. (2016). Phyllodes tumours of the breast: a consensus review. Histopathology, 68(1), 5-21. DOI: 10.1111/his.12876. [PMC free article] [PubMed] [CrossRef] [Google Scholar]

Shubham, S., Ahuja, A., & Bhardwaj, M. (2019). Immunohistochemical expression of Ki-67, p53, and CD10 in phyllodes tumor and their correlation with its histological grade. Journal of Laboratory Physicians, 11(04), 330-334. https://doi.org/10.4103%2FJLP.JLP_106_19

Network NCC (2022). NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines) Breast Cancer. https://www.nccn.org/professionals/physician_gls/pdf/breast.pdf

Lavoué, V., Fritel, X., Antoine, M., Beltjens, F., Bendifallah, S., Boisserie-Lacroix, M., ... & of Gynecologists, F.C. (2016). Clinical practice guidelines from the French College of Gynecologists and Obstetricians (CNGOF): benign breast tumors–Short Text. European Journal of Obstetrics & Gynecology and Reproductive Biology, 200, 16-23. DOI: 10.1016/j.ejogrb.2016.02.017. [PubMed] [CrossRef] [Google Scholar]

Diego, E.J., Rosenberger, L.H., Deng, X., & McGuire, K.P. (2022). Margin management and adjuvant therapy for phyllodes tumors: practice patterns of the american society of breast surgeons members. Annals of Surgical Oncology, 29(10), 6151-6161. DOI: 10.1245/s10434-022-12192-x. [PubMed] [CrossRef] [Google Scholar]

Tan, P.H., Ellis, I., Allison, K., Brogi, E., Fox, S.B., Lakhani, S., ... & Cree, I.A. (2020). The 2019 WHO classification of tumours of the breast. Histopathology, 77(2),181–185. DOI: 10.1111/his.14091. [PubMed] [CrossRef] [Google Scholar]

Rosenberger, L.H., Thomas, S.M., Nimbkar, S.N., Hie­ken, T.J., Ludwig, K.K., Jacobs, L.K., ... & Jakub, J.W. (2021). Contemporary multi-institutional cohort of 550 cases of phyllodes tumors (2007-2017) demonstrates a need for more individualized margin guidelines. Journal of Clinical Oncology, 39(3), 178. DOI: 10.1200/JCO.20.02647. [PMC free article] [PubMed] [CrossRef] [Google Scholar]

Galaychuk, I., Nitefor, L., & Perepyolkina, I. (2017). Bilateral Breast Sarcoma In Women With Macromastia. EUREKA: Health Sciences, (4), 49-54.

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Published

2023-07-25

How to Cite

Nitefor, L. V., Halaichuk, I. Y., Tumanova, O. R., Miklashevska, O. A., Karashivska, O. S., Uglyar, T. Y., & Uglyar, Y. V. (2023). Clinical case of diagnosis and surgical treatment of malignant phyllodes tumor of the breast. Hospital Surgery. Journal Named by L.Ya. Kovalchuk, (2), 84–87. https://doi.org/10.11603/2414-4533.2023.2.13997

Issue

No. 2 (2023)

Section

REPORTS

License

Copyright (c) 2023 Л. В. Нітефор, І. Й. Галайчук, О. Р. Туманова, О. А. Міклашевська, О. С. Карашівська, Т. Ю. Угляр, Ю. В. Угляр

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