Surgical aspects of treatment cancer of the distal part of the stomach, Complicated by perforation, stenosis and acute bleeding

Authors

  • O. B. Prudnikova O. Bohomolets National Medical University Kyiv
  • P. V. Ivanchov O. Bohomolets National Medical University Kyiv

DOI:

https://doi.org/10.11603/2414-4533.2022.2.13167

Keywords:

cancer of the distal part of the stomach, surgical treatment; stenosis, perforation, acute bleeding

Abstract

The aim of the work – to improve the results of surgical treatment of cancer of the distal part of the stomach, complicated by perforation, stenosis and acute bleeding.

Materials and Methods. In the period from 2006 to 2020, 766 patients with malignant stomach tumors were treated at the clinic, which were complicated by acute bleeding, stenosis or perforation of tumors, which was 2.5 % of all patients treated for gastrointestinal bleeding during the work of the center. Cancer of the distal part of the stomach occurred in 247 (32.2 %) patients, among whom the course of the disease was complicated by the development of acute bleeding in 193 (78.1 %); bleeding and stenosis – in 103 (41.7 %); perforation – in 54 (21.9 %); perforations and stenosis – in 35 (14.2 %); bleeding, perforations and stenosis – in 28 (11.3 %). The age of 173 (70.0 %) men and 74 (30.0 %) women was from 19 to 90 years, and the largest number of patients was noted in the age groups of 61–70 years – 76 (30.7 %) and 71–80 years – 62 (25.1 %) patients. The ratio of men to women was 2.4:1.

Results and Discussion. In total, out of 247 patients, 115 (46.6 %) were operated on: on the background of bleeding – 61 (53.0 %); bleeding and stenosis 52 (45.2 %); perforations – 54 (46.9 %); perforations and stenosis – 35 (30.4%); bleeding, stenosis and perforation – 28 (24.3 %). In the group of patients with newly diagnosed cancer, operative activity was 49.2 % (63 out of 128). Radical operations were performed in 81 (70.4 %) patients, palliative and symptomatic operations were performed in 34 (29.6 %) patients. Lymphodisection D1 was performed during 7 (8.6 %) radical operations, D2 – 74 (91.4 %). The total postoperative mortality was 6.9 % (8 patients). 4 (3.5 %) patients died after radical surgical interventions, and 5 (14.7 %) – after palliative and symptomatic operations. Five-year survival after radical surgery was 44.5 %, and 10-year survival was 8.9 %, with a median survival of 29 months.

References

Kondratenko, P.H., & Smyrnov, M.L. (2011). Hostra krovotecha z novoutvoren travnoho kanalu: taktychni pidkhody [Acute bleeding from neoplasms of the alimentary canal: tactical approaches]. Ukrainskyi zhurnal khirurhii – Ukrainian Journal of Surgery, 1, 144-149 [in Ukrainian].

Bubniak, M.R. (2019). Endovaskuliarna diahnostyka, likuvannia i profilaktyka hostrykh hastro-duodenalnykh krovotech [Endovascular diagnosis, treatment and prevention of acute gastro-duodenal bleeding]. Extended abstract of Candidate’s thesis. Universitatis Medicinalis Leopoliensis. Lviv [in Ukrainian].

Bratus, V.D. (1991). Dyfferentsyalnaya diagnostika i lechenye ostrykh zheludochno-kyshechnыkh krovotechenyi [Differential diagnosis and treatment of acute gastrointestinal bleeding]. Kyiv: Zdorovia [in Russian].

Bratus, V.D. (2001). Novye tendentsii v lechenii bolnykh s ostrymi zheludochno-kyshechnymi krovotecheniyamy [New trends in the treatment of patients with acute gastrointestinal bleeding], Ukrainskyi zhurnal maloinvazyvnoi ta endoskopichnoi khirurhii – Ukrainian Journal of Minimally Invasive and Endoscopic Surgery, 1, 5-6 [in Russian].

Borbashev, T.T. (2018). Morfologicheskaya harakteristika oslozhnenogo raka zheludka (Perforatsiya, raspad) [Morphological characteristics of complicated cancer (Perforation, decay)]. Zdravookhraneniye Kyrgyzstana – Healthcare of Kyrgyzstan, 3, 29-32 [in Russian].

Nevozhay, V.I., Fedorenko, T.A., & Khudchenko, Ye.V. (2014). Neposredstvennyye rezultaty khirurgicheskogo lecheniya bolnykh rakom zheludka [Immediate results of surgical treatment of patients with gastric cancer.]. Tikhookeanskiy meditsinskiy zhurnal – Pacific Medical Journal, 1, 52-55 [in Russian].

Fomin, P.D., & Ivanchov, P.V. (2011). Khirurhichna taktyka pry hostrokrovotochyvykh zloiakisnykh pukhlynakh shlunka [Surgical tactics in acutely bleeding malignant tumors of the stomach]. Kharkivska khirurhichna shkola – Kharkiv Surgical School, 1, 9-14 [in Ukrainian].

Wang, S.Y., Hsu, C.H., Liao, C.H., Fu, C.Y., Ouyang, C.H., Cheng, C.T., ... & Yeh, C.N. (2017). Surgical outcome evaluation of perforated gastric cancer: from the aspects of both acute care surgery and surgical oncology. Scandinavian Journal of Gastroenterology, 52 (12), 1371-1376.

Lee, N.K., Kim, S., Hong, S.B., Lee, S.J., Kim, T.U., Ryu, H., ... & Suh, H.B. (2020). CT diagnosis of non-traumatic gastrointestinal perforation: an emphasis on the causes. Japanese Journal of Radiology, 38 (2), 101-111 DOI: 10.1007/s11604-019-00910-7.

Yang, L., Ying, X., Liu, S., Lyu, G., Xu, Z., Zhang, X., ... & Ji, J. (2020). Gastric cancer: Epidemiology, risk factors and prevention strategies. Chinese Journal of Cancer Research, 32 (6), 695.

Published

2022-09-14

How to Cite

Prudnikova, O. B., & Ivanchov, P. V. (2022). Surgical aspects of treatment cancer of the distal part of the stomach, Complicated by perforation, stenosis and acute bleeding. Hospital Surgery. Journal Named by L.Ya. Kovalchuk, (2), 5–9. https://doi.org/10.11603/2414-4533.2022.2.13167

Issue

Section

ORIGINAL INVESTIGATIONS