Bariatric embolization of gastric arteries in the experiment

Authors

  • I. Ya. Dziubanovskyi I. Horbachevsky Ternopil National Medical University
  • A. M. Prodan I. Horbachevsky Ternopil National Medical University
  • M. Yu. Kritsak I. Horbachevsky Ternopil National Medical University
  • B. M. Masliy I. Horbachevsky Ternopil National Medical University

DOI:

https://doi.org/10.11603/2414-4533.2022.1.12916

Keywords:

bariatric embolization, leptin, ghrelin

Abstract

The aim of the work: to evaluate the effectiveness of bariatric embolization of gastric arteries in experimental animals by the dynamics of changes in mass, serum levels of ghrelin and leptin.

Materials and Methods. For the experiment, 10 Vietnamese pigs aged 4–5 months, females, were selected, which were on a high fat diet for 2 months. Animals weighing more than 30 % of baseline were considered obese. The control group consisted of 5 animals of the same sex and age, which were kept in standard conditions and a normal diet. Bariatric embolization of the left gastric artery was performed. Measurements of body weight dynamics were performed 1 and 3 months after BEA surgery. Serum levels (2 ml venous blood samples) of ghrelin and leptin were also determined before and 1.3 months after surgery using appropriate ELISA kits.

Results and Discussion. Analysis of the dynamics of body weight revealed its reduction in experimental animals after 3 months by 16.05 % of the preoperative rate (p˂0.001). The dynamics of serum ghrelin levels showed a decrease after 3 months of follow-up after BEA by 23.79 % of preoperative values ​​(p˂0.001) and leptin levels by 56.38 % (p˂0.001).

References

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Published

2022-05-20

How to Cite

Dziubanovskyi, I. Y., Prodan, A. M., Kritsak, M. Y., & Masliy, B. M. (2022). Bariatric embolization of gastric arteries in the experiment. Hospital Surgery. Journal Named by L.Ya. Kovalchuk, (1), 36–39. https://doi.org/10.11603/2414-4533.2022.1.12916

Issue

No. 1 (2022)

Section

EXPERIMENTAL INVESTIGATIONS

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