Endoscopic-morphological assessment of hemostasis in bleeding Gastrododenal ulcers
DOI:
https://doi.org/10.11603/2414-4533.2021.4.12717Keywords:
endoscopic hemostasis, gastroduodenal ulcer, bleedingAbstract
The aim of the work: to evaluate endoscopic and morphological criteria of bleeding activity with prediction of the probability of its recurrence in the case of chronic active gastroduodenal ulcer.
Materials and Methods. The endoscopic picture in 378 patients with chronic bleeding ulcers of the stomach and duodenum according to the Forrest classification was analyzed. There were 257 male patients (67.98 %) and 121 female patients (32.02 %). Of Forest IA, IB, IIA, IIB, IIS, there were 231 (61.11 %) patients who underwent endoscopic hemostasis (injection therapy or argonoplasmic coagulation). In 147 (38.89 %) patients, hemostasis was not performed due to the endoscopic picture of bleeding activity in Forest III. Biopsy was taken from the area of periulcerative infiltrate during endoscopic diagnosis before hemostasis on the day of admission to the hospital. Histological material was fixed in formalin solution, prepared microscopic slides stained with hematoxylin and eosin. The calculation of the study data was performed on the basis of the use of standard software products “Statistica”.
Results and Discussion. A comparative evaluation of endoscopic hemostasis methods revealed the advantages of argonoplasmic coagulation over injection methods, which can be interpreted as the “gold standard” when choosing the method of endoscopic hemostasis. The prospect of the study is the choice of surgical tactics depending on the prognosis of the likelihood of recurrence of bleeding, depending on the quantitative ratio of reparative and destructive cells in biopsies of ulcerative infiltration in patients with unstable hemostasis.
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